What is the difference between C57BL 6 and BALB C?
BALB/c mice tend to produce a stronger humoral response than C57BL/6 mice. These strains have different gene sequences at the H2 site of the major histocompatibility (MHC)class I gene locus – BALB/c mice is H2d, while C57BL/6 is H2b. The difference in gene sequence of these two strains falls on the H2 locus.
What does BALB C stand for?
BALB/c
BALB/c is an albino, immunodeficient inbred strain. BALB refers to Bagg Albino (inbred research mouse strain. Dr. Halsey J. Bagg who started breeding these mice back in the 1920s.
Are BALB c mice wild type?
BALB/c is an albino, laboratory-bred strain of the house mouse from which a number of common substrains are derived.
How old is a 2 year old mouse in human years?
How many ‘human years’ is one ‘mouse year’? The average lifespan of a laboratory mouse is about two years, while the average human lives about 80 years. This would make one mouse day roughly equivalent to 40 human days, while one human year equates to about 9 mouse days.
What is the oldest mouse?
Andrzej Bartke, a research professor at Southern Illinois University School of Medicine in Springfield, won the Methuselah Mouse Prize, awarded by the nonprofit Methuselah Foundation, in 2003 for the oldest ever mouse, a mutant dwarf mouse that died six days short of its fifth birthday. “He was exceptional.
How are C57BL / 6 ES cells used in research?
C57BL/6 mice are most commonly used as the genetic background of our mouse models. C57BL/6 ES cells are used to create transgenic mouse models. When a project calls for ES cell technology, we offer an integrated solution for genetic manipulation of ES cells and injections into embryos for reimplantation into foster females.
Which is the host blastocyst for C57BL / 6 es?
The clonal embryonic stem cell line #693 ES C57BL/6 was derived from a strain C57BL/6J (B6) mouse blastocyst [PubMed: 11730008]. The ES cells were shown to populate the germ line of two host blastocyst donors, FVB/NJ (FVB) and the coisogenic strain C57BL/6-Tyrc-2J (c2J).
What kind of stem cell is es 693?
The clonal embryonic stem cell line #693 ES C57BL/6 was derived from a strain C57BL/6J (B6) mouse blastocyst ref. The ES cells were shown to populate the germ line of two host blastocyst donors, FVB/NJ (FVB) and the coisogenic strain C57BL/6-Tyrc-2J (c2J).
Can a MEF be cultured with es-c57bl / 6?
ATCC recommends culturing ES-C57BL/6 on mouse embryonic fibroblasts (MEFs) that have been mitotically arrested by either irradiation or treatment with Mitomycin-C. ES-C57BL/6 cells have been cultured on mitotically arrested MEF (CF-1) (ATCC ® SCRC-1040™).