What is keratosis Follicularis?
Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder. Affected individuals develop skin lesions that consist of thickened, rough bumps (papules) or plaques that may also be greasy or have a brown or yellow crust.
What does Darier’s disease look like?
Darier disease is a skin condition characterized by wart-like blemishes on the body. The blemishes are usually yellowish in color, hard to the touch, mildly greasy, and can emit a strong odor. The most common sites for blemishes are the scalp, forehead, upper arms, chest, back, knees, elbows, and behind the ear.
Is keratosis a disability?
Common skin lesions like impetigo, actinic keratosis, and seborrheic keratosis are never disabling and are not in Social Security’s Listing of Impairments.
Can keratosis cause baldness?
Keratosis pilaris atrophicans is a rare variant of keratosis pilaris, which is characterized by hair loss and follicular depressions that look like scars.
Is Darier’s disease painful?
Manifestations usually begin at childhood or adolescence. Characteristic lesions are hyperkeratotic, erythematous, pruritic plaques that may ulcerate, scale and turn gray, get crusted, or coalesce into larger lesions. They may become extremely painful and foul-smelling, especially if there is a superimposed infection.
Is keratosis inherited?
Is keratosis pilaris hereditary? It is usually found in more than one member of a family. The way it is inherited varies from family to family, but it often fits into an ‘autosomal dominant’ pattern. This means that there will be a 1 in 2 chance that each child of an affected parent will inherit the condition.
Is keratosis a virus?
A seborrheic keratosis is a noncancerous (benign) growth on the skin. It’s color can range from white, tan, brown, or black. Most are raised and appear “stuck on” to the skin. They may look like warts.
What is alopecia Mucinosa?
Alopecia mucinosa, also known as Pinkus’ follicular mucinosis or mucinosis follicularis is an abnormal accumulation of a normal substance, mucin, in hair bearing skin.
What is keratosis of the scalp?
A seborrheic keratosis (seb-o-REE-ik ker-uh-TOE-sis) is a common noncancerous skin growth. People tend to get more of them as they get older. Seborrheic keratoses are usually brown, black or light tan. The growths look waxy, scaly and slightly raised. They usually appear on the head, neck, chest or back.
How is Darier disease treated?
Severe Darier disease is usually treated with oral retinoids, either acitretin or isotretinoin. Ciclosporin has been reported to be effective in a few patients.
Is Darier disease contagious?
It is not due to an allergy and it is not contagious (catching). Darier disease is often aggravated by heat, sunlight, skin friction, excessive sweating, and it can make the skin more prone to infection. Some females may notice their skin flares before their period.
What kind of skin lesions does keratosis follicularis cause?
General Discussion Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder. Affected individuals develop skin lesions that consist of thickened, rough bumps (papules) or plaques that may also be greasy or have a brown or yellow crust.
What are the symptoms of keratosis follicularis Darier?
Although in most people Darier disease is limited to the skin, additional symptoms have been reported in some cases including seizures, bipolar disorder, and learning disabilities. Keratosis follicularis may -be restricted to a band of skin on one side of the body (segmental or linear keratosis follicularis).
Who is the dermatologist for keratosis follicularis Nord?
NORD gratefully acknowledges Dr. Susan Burge, Honorary Consultant Dermatologist, Oxford University Hospitals NHS Trust, United Kingdom, for assistance in the preparation of this report. Keratosis follicularis, also known as Darier disease, is a rare, genetic skin disorder.
How are oral retinoids used to treat keratosis follicularis?
Retinoids taken by mouth (orally) have been effective in treating individuals with keratosis follicularis and are the drugs most often used to treat severe cases. Oral retinoids such as tretinoin and acitretin affect the entire body (systemic therapy). Oral retinoids can be associated with side effects.