What is daclatasvir used for?
Daclatasvir is used along with another medication (sofosbuvir [Solvadi]) to treat a certain type of chronic hepatitis C (an ongoing viral infection that damages the liver). Daclatasvir is in a class of antiviral medications called hepatitis C virus (HCV) NS5A inhibitors.
Why was daclatasvir discontinued?
The FDA issued a complete response letter for NS5A inhibitor daclatasvir saying it was unable to approve the drug because the marketing application was for its use in tandem with asunaprevir, an NS3/NS4A protease inhibitor discontinued in the US by BMS last month for commercial reasons.
What are common side effects of daclatasvir?
Common side effects of Daklinza include:
- headache,
- fatigue,
- nausea,
- diarrhea,
- low levels of iron in the blood (anemia),
- rash,
- insomnia,
- dizziness, and.
How do I take sofosbuvir and daclatasvir?
The recommended standard dose of daclatasvir is 60 mg orally once daily, with or without food. The recommended dose of sofosbuvir, when used with daclatasvir is 400 mg once daily, with or without food.
Who makes Daclatasvir?
Bristol-Myers Squibb Company
Bristol-Myers Squibb Company (NYSE:BMY) announced today that Daklinza™ (daclatasvir, 60 mg), an NS5A replication complex inhibitor, has been approved by the U.S. Food and Drug Administration (FDA) in combination with sofosbuvir (with or without ribavirin) in genotypes 1 and 3.
What kind of Medicine is daclatasvir used for?
From Wikipedia, the free encyclopedia Daclatasvir, sold under the trade name Daklinza, is a medication used in combination with other medications to treat hepatitis C (HCV). The other medications used in combination include sofosbuvir, ribavirin, and interferon, vary depending on the virus type and whether the person has cirrhosis.
Can you take daclatasvir without sofosbuvir?
Daclatasvir should never be used without sofosbuvir. Daclatasvir and sofosbuvir may also be used with another antiviral medication (ribavirin). These medications together reduce the amount of hepatitis C virus in your body, which helps your immune system fight the infection and may help your liver recover.
How to report side effects of daclatasvir in Canada?
You may report side effects to Health Canada at 1-866-234-2345. Before taking daclatasvir, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems.
How much does a course of daclatasvir cost?
Cost and Medication Access. The wholesale acquisition cost (WAC) cost for a 12-week course of daclatasvir is $63,000. Bristol-Myers Squibb has a program for support and financial help related to medication access; see the web site Patient Support Connect, which has information for both patients and professionals.