Is iodination the same as Organification?
Iodination of tyrosines on thyroglobulin (also known as “organification of iodide”).
What is Organification thyroid hormone?
Organification is a biochemical process that takes place in thyroid gland. It is the incorporation of iodine into thyroglobulin for the production of thyroid hormone, a step done after the oxidation of iodide by the enzyme thyroid peroxidase (TPO).
What stimulates thyroglobulin synthesis?
When stimulated by thyroid stimulating hormone (TSH), the colloid is endocytosed from the follicular lumen into the surrounding thyroid follicular epithelial cells. The colloid is subsequently cleaved by proteases to release thyroglobulin from its T3 and T4 attachments.
What is an iodination reaction?
Iodination: Any reaction or process in which iodine (and no other elements) are introduced into a molecule. Iodination of tert-butylbenzene by electrophilic aromatic substitution. Enolate iodination is part of the iodoform reaction.
How long is iodine stored in the thyroid?
The thyroid hormones are stored inside the thyroid follicles as colloid for several months. The stored hormones can meet the body requirements for up to 3 months (3,4).
How does iodination occur?
Spontaneous iodination of tyrosine residues in proteins occurs in the iodine-rich marine environment. Subsequent coupling of two iodinated tyrosines and digestion of proteins may release iodothyronines, including T4 and T3, and these thyroid hormones are indeed found in significant amounts in marine invertebrates.
What is iodination used for?
Iodization of salt can be utilized throughout the food chain (universal salt iodization). This is the ideal strategy for correcting iodine deficiency however certain challenges need overcoming. Key challenges include overcoming reluctance from industry and lack of ongoing political support.
How quickly does iodine leave the body?
The radioiodine from your treatment will temporarily remain in your body. Most of the radioiodine not taken up by your thyroid gland will be eliminated within the first (2) two days after treatment. Radioiodine leaves your body primarily by your urine. Very small amounts may leave in your saliva, sweat, or feces.
How does your reaction time affect your performance?
Reaction time is linked to performance in many sports and video games, and improving yours has many positive effects. A lack of sleep can have a huge effect on your reflexes and split-second decision making.
How is reaction time related to perception and process?
In this example, the processes (perceive, process, and respond), are done in a matter of milliseconds, but reaction time can vary depending on a variety of factors: Complexity of the stimulus- The more complex the stimulus, the more information that has to be processed, the longer this process will take.
What’s the average reaction time for a human being?
The average (median) reaction time is 215 milliseconds, according to the data collected so far.
What can I do to improve my reaction time?
alcoholic drinks, and getting 8 hours or more a night is recommended. Training your hand-eye coordination, playing sports, staying physically active, and playing high paced FPS games are great activities which will help you improve your reaction time.