Who manufactures pramipexole?
Dr. Reddy’s Laboratories announced the launch of Pramipexole Dihydrochloride Extended-Release Tablets, the generic version of Boehringer Ingelheim’s Mirapex ER. Mirapex ER is a non-ergot dopamine agonist indicated for idiopathic Parkinson’s disease.
What is the brand name for pramipexole?
Pramipexole oral tablets are available as both generic and brand-named drugs. Brand names: Mirapex and Mirapex ER. Pramipexole tablets come in immediate-release and extended-release forms you take by mouth. Pramipexole immediate-release and extended-release tablets are used to treat Parkinson’s disease.
How do you pramipexole titrate?
Titration: Increase gradually no more frequently than every 5 to 7 days, first dose increase should be to 0.75 mg once a day followed by incremental increases of 0.75 mg; assess therapeutic response and tolerability at a minimum of 5 days after each dose increase.
Is pramipexole the same as sifrol?
Sifrol contains the active ingredient pramipexole dihydrochloride monohydrate. It belongs to a group of medicines known as dopamine agonists, which bind to dopamine receptors. It is believed that Sifrol works by having a similar effect as dopamine in the brain.
What is generic for pramipexole?
Pramipexole diHCl tablets are available in a 0.125-mg strength, in a bottle size of 63, and in 0.25-mg, 0.5-mg, 1-mg, and 1.5-mg strengths, in bottle sizes of 90. The generic is equivalent to Mirapex, which was developed by Boehringer Ingelheim Pharmaceuticals.
Who manufactures Requip?
Requip, made by GlaxoSmithKline, is used to treat restless legs syndrome and Parkinson’s disease.
What is equivalent to pramipexole?
Levodopa equivalent daily dose conversion factors5
| Drug | Conversion factor |
|---|---|
| Entacapone | LD x 0.33 |
| Tolcapone | LD x 0.5 |
| Pramipexole | x 100 |
| Ropinirole | x 20 |
Why do you titrate pramipexole?
Prolonged dose titration is required to minimize nausea in particular, the most common side effect of dopamine agonists including pramipexole. This strategy is particularly important in countries such as the United States where the dopamine antagonist domperidone is not FDA approved or readily available.
What are the dosages of pramipexole?
The starting dosage of pramipexole is 0.125 mg taken once daily two to three hours before bedtime. If needed, the dosage may be doubled every four to seven days up to a maximal dosage of 0.5 mg daily.
Does pramipexole make you gain weight?
Physicians should be aware that compulsive eating resulting in significant weight gain may occur in PD as a side-effect of dopamine agonist medications such as pramipexole. Given the known risks of the associated weight gain and obesity, further investigation is warranted.