Which of the following patients qualify for the Xpert MTB RIF assay test?
Xpert MTB/RIF should be used as the initial diagnostic test rather than conventional microscopy, culture and DST in all persons living with HIV who have signs or symptoms of TB, in persons who are seriously ill and suspected of having TB regardless of their HIV status, and in those whose HIV status is unknown but who …
What is GeneXpert test?
Abstract. Introduction: Gene-Xpert, a CBNAAT (catridge based nucleic acid amplification test) is a widely accepted diagnostic test for Tuberculosis. This test is a rapid diagnostic test for Tuberculosis detection as well as Rifampicin resistance in direct smear negative cases.
What is MTB RIF test?
The Xpert MTB/RIF assay is a new test that is revolutionizing tuberculosis (TB) control by contributing to the rapid diagnosis of TB disease and drug resistance. The test simultaneously detects Mycobacterium tuberculosis complex (MTBC) and resistance to rifampin (RIF) in less than 2 hours.
What is MTB trace detected?
The “MTB Detected, trace”, henceforth referred to as “trace call” indicates that only the multi-copy targets were detected, and not the TB specific regions in the rpoB gene.
What is Xpert MTB RIF Ultra?
Background. The Xpert MTB/RIF assay is an automated molecular test that has improved the detection of tuberculosis and rifampicin resistance, but its sensitivity is inadequate in patients with paucibacillary disease or HIV. Xpert MTB/RIF Ultra (Xpert Ultra) was developed to overcome this limitation.
Is Xpert MTB RIF PCR?
The Xpert MTB/RIF assay, using real-time PCR for the TB-specific rpoB gene, is a cartridge-based, automated diagnostic test that can simultaneously identify MTB and resistance to rifampin; it was recently introduced for the rapid diagnosis of TB in Korea.
Is MTB curable?
Tuberculosis, also known as TB, is an airbone infectious disease caused by the bacteriumMycobacterium tuberculosis that is preventable and curable.
What is the limit of detection LOD of GeneXpert MTB RIF?
131 CFU/ml
The analytical limit of detection of the GeneXpert assay is reported to be 131 CFU/ml of specimen, based on spiked-sputum studies (3). Culture of concentrated specimens can detect very low concentrations of organisms—as low as 10 to 100 CFU/ml (1).
What are the targets in the Xpert MTB RIF Ultra test?
To improve assay sensitivity in the detection of Mycobacterium tuberculosis complex, Xpert Ultra incorporates two different multicopy amplification targets (IS6110 and IS1081) and uses improved assay chemistry and cartridge design.
How accurate is GeneXpert for Covid 19?
We found that the sensitivity of the Xpert Xpress SARS-CoV-2 assay was 100% (20 of 20) and the specificity was 80% (16 of 20).
How does the Xpert MTB / RIF assay work?
The Xpert MTB/RIF assay is a new test that is revolutionizing tuberculosis (TB) control. by contributing to the rapid diagnosis of TB disease and drug resistance. The test simultaneously detects. Mycobacterium tuberculosis. complex (MTBC) and resistance to rifampin (RIF) in less than 2 hours.
What kind of test is Cepheid Xpert HCV viral load?
Cepheid’s Xpert HCV Viral Load is a quantitative test that provides on-demand molecular testing for diagnosis and monitoring of HCV. You are using an unsupported browser.
Do you have to have MTBC to test for Rif?
Regardless of the Xpert MTB/RIF result, patient specimens should also have mycobacterial culture to ensure isolates are available for drug susceptibility testing and genotyping. Results that are positive for MTBC and for RIF resistance mean that the bacteria have a high probability of resistance to RIF.
How does the Xpert viral load test work?
Xpert HCV Viral Load is a quantitative test that provides on-demand molecular testing for diagnosis* and monitoring of HCV. Based on the GeneXpert ® technology, Xpert HCV Viral Load utilises automated reverse transcriptase polymerase chain reaction (RT-PCR) using fluorescence to detect and quantify RNA.