Which antibiotics are protein synthesis inhibitors?
Protein Synthesis Inhibitors
- Tetracycline and glycylcycline.
- Oxazolidinones.
- Amphenicols and pleuromutilins.
- Macrolides and ketolides.
- Lincosamides.
- Streptogramins.
What drugs are protein synthesis inhibitors?
INTRODUCTION. Bacteriostatic protein-synthesis inhibitors that target the ribosome, such as tetracyclines and gly-cylcyclines, chloramphenicol, macrolides and ketolides, lincosamides (clindamycin), streptogramins (quinupristin/dalfopristin), oxazolidinones (linezolid), and aminocyclitols (spectinomycin).
Which antibiotic does not inhibit protein synthesis?
Peptidyl transferase is a key enzyme involved in translocation, the final step in the peptide elongation cycle. Lincomycin and clindamycin are specific inhibitors of peptidyl transferase, while macrolides do not directly inhibit the enzyme.
What class of antibiotics work by inhibiting protein synthesis?
A third group of substances inhibit growth and M protein synthesis at the same concentration. These substances probably inhibit growth because they inhibit general protein synthesis, and are therefore specific inhibitors of protein synthesis. In this class are chloramphenicol, erythromycin, and the tetracyclines.
Which antibiotic is bacterial cell wall synthesis inhibitor?
Penicillins and cephalosporins are the major antibiotics that inhibit bacterial cell wall synthesis. They are called beta-lactams because of the unusual 4-member ring that is common to all their members.
What bacteria does co-Amoxiclav cover?
Pseudomonas spp. Serratia spp. Stenotrophomas maltophilia Yersinia enterolitica Others: Chlamydia pneumoniae Chlamydia psittaci Chlamydia spp. Coxiella burnetti Mycoplasma spp.
Which class of antibiotics works by inhibiting protein synthesis?
This drug acts to inhibit bacterial protein and DNA synthesis. Puromycin is an antibiotic that prevents bacterial protein translation….Protein Synthesis Inhibitors.
| Drug | Target | Type |
|---|---|---|
| Chloramphenicol | Chloramphenicol acetyltransferase | enzyme |
| Chloramphenicol | Chloramphenicol 3-O phosphotransferase | enzyme |
| Linezolid | 23S ribosomal RNA | target |
Which bacteria acts by inhibiting protein synthesis?
Aminoglycosides are protein synthesis inhibitors that act primarily by impairing bacterial protein synthesis through binding to prokaryotic ribosomes. Several mechanisms of aminoglycoside resistance have been described in Gram-positive and Gram-negative bacteria.
Which antibiotics inhibit cell wall synthesis?
Penicillins and cephalosporins are the major antibiotics that inhibit bacterial cell wall synthesis.