What type of gene is CEBPg?
CEBPG (CCAAT Enhancer Binding Protein Gamma) is a Protein Coding gene.
Where is the CEBPA gene located?
| CEBPA | ||
|---|---|---|
| Location (UCSC) | Chr 19: 33.3 – 33.3 Mb | Chr 7: 35.12 – 35.12 Mb |
| PubMed search | ||
| Wikidata | ||
| View/Edit Human View/Edit Mouse |
What is the CEBPA gene?
The CEBPA gene provides instructions for making a protein called CCAAT enhancer-binding protein alpha. This protein is a transcription factor, which means that it attaches (binds) to specific regions of DNA and helps control the activity (expression) of certain genes.
Is CEBPB a transcription factor?
Function. The protein encoded by this intronless gene is a bZIP transcription factor that can bind as a homodimer to certain DNA regulatory regions. It can also form heterodimers with the related proteins CEBP-alpha, CEBP-delta, and CEBP-gamma.
What chromosome is the Cebpa gene on?
CCAAT Enhancer Binding Protein Alpha (CEBPA) is an intronless gene located on chromosome 19q13. 15,6. It encodes protein belonging to transcription factors family containing a basic leucine zipper (bZIP) motif6,7.
What is gata 2 mutation?
GATA2 deficiency is a rare disorder of the immune system with wide-ranging effects. First identified in 2011, the disorder is char- acterized by immunodeficiency, myelodys- plastic syndrome (a condition characterized by ineffective blood cell production), lung dis- ease, and problems of the vascular/lymphatic system.
What is GATA2 Haploinsufficiency?
The mechanism underlying GATA2 deficiency is called “haploinsufficiency.” This means that having one mutated copy of GATA2 and one working copy of GATA2 is insufficient for normal functioning of the hematopoietic, or blood- making, system.
How is ATF3 protein produced?
for example, found that ATF3 is induced by proinflammatory cytokines, glucose, and palmitate in ß cells (25). ATF3 induction is partially mediated by the NF-κB and JNK/stress-activated protein kinase (SAPK) signaling pathways, which are two stress-induced pathways involved in diabetes.