What is the survival rate of Angioimmunoblastic T-cell lymphoma?
Angioimmunoblastic T-cell lymphoma is typically aggressive with a median survival of fewer than 3 years, even with intensive treatment. Patients usually present with late stage III-IV disease, and survival rates have been quoted as being 33% 5 years and 29% at 7 years [18].
What is the survival rate of T-cell lymphoma?
The 3-year survival rate of the whole group was 45% with a median follow-up of 28 months. The 3-year survival rates of chemoradiotherapy, chemotherapy, and radiotherapy groups were 56%, 38%, and 25%, respectively.
What does Angioimmunoblastic T-cell lymphoma mean?
Listen to pronunciation. (AN-jee-oh-IH-myoo-noh-BLAS-tik T-sel lim-FOH-muh) An aggressive (fast-growing) type of T-cell non-Hodgkin lymphoma marked by enlarged lymph nodes and hypergammaglobulinemia (increased antibodies in the blood).
What’s the cause of Angioimmunoblastic T-cell lymphoma?
These types of lymphoma usually affect older people, typically around the age of 70. They affect men and women equally. Scientists don’t know what causes AITL or FTCL. They seem to be linked to infection with viruses called Epstein-Barr virus (EBV) and human herpesvirus 6 (HHV-6).
Is AITL curable?
AITL can occasionally spontaneously remit, though almost never does so permanently. The complete remission rate with CHOP is 64% with a median survival of 19 months. The 5 year overall survival is 32% with a 5 year failure free survival of 18%.
Is AITL lymphoma curable?
In general, relapsed lymphoma remains potentially curable; however, required approaches are significantly more aggressive and therefore riskier than the initial treatment. AITL cure remains elusive in the majority of patients.
Can Angioimmunoblastic cell lymphoma be cured?
Where does Angioimmunoblastic T-cell lymphoma affect?
Lymph nodes in the neck, armpit and groin are most often affected. Another symptom sometimes associated with AITL is the development of a distinctive skin rash that may or may not be itchy (pruritic).
Is AITL hereditary?
AITL accounts for 1-2% of cases of non-Hodgkin lymphoma overall. AITL predominantly affects older individuals, with a median age at diagnosis of approximately 60. There is a slight male predominance. There are no identified genetic or environmental risk factors.
What does Angioimmunoblastic mean?
What Does Angioimmunoblastic Mean? The term angio refers to blood vessels. This lymphoma has certain unusual features including an increase in the number of small abnormal blood vessels in the body parts that are affected. ‘Immunoblast’ is a term used for an immature immune cell (or lymph cell).