What is the mode of action of thyroxine?
Thyroxine is released from its precursor protein thyroglobulin through proteolysis and secreted into the blood where is it then peripherally deiodinated to form triiodothyronine (T3) which exerts a broad spectrum of stimulatory effects on cell metabolism.
What does the drug thyroxine do?
Thyroxine controls how much energy your body uses (the metabolic rate). It’s also involved in digestion, how your heart and muscles work, brain development and bone health. When the thyroid gland does not make enough thyroxine (called hypothyroidism), many of the body’s functions slow down.
What is the main effect of thyroxine?
Thyroxine is the main hormone secreted into the bloodstream by the thyroid gland. It plays vital roles in digestion, heart and muscle function, brain development and maintenance of bones.
What is the description of thyroxine?
A hormone that is made by the thyroid gland and contains iodine. Thyroxine increases the rate of chemical reactions in cells and helps control growth and development. Thyroxine can also be made in the laboratory and is used to treat thyroid disorders. Also called L-3,5,5′-tetraiodothyronine, T4, and thyroxin.
What does the thyroid do?
The thyroid controls your metabolism with a few specific hormones — T4 (thyroxine, contains four iodide atoms) and T3 (triiodothyronine, contains three iodide atoms). These two hormones are created by the thyroid and they tell the body’s cells how much energy to use.
What is the function of thyroid hormone?
Thyroid hormones affect every cell and all the organs of the body. They: Regulate the rate at which calories are burned, affecting weight loss or weight gain. Can slow down or speed up the heartbeat.
What does a thyroid do?
Your thyroid has an important job to do within your body — releasing and controlling thyroid hormones that control metabolism. Metabolism is a process where the food you take into your body is transformed into energy. This energy is used throughout your entire body to keep many of your body’s systems working correctly.
What are functions of thyroid hormones?
Function. The thyroid hormones act on nearly every cell in the body. It acts to increase the basal metabolic rate, affect protein synthesis, help regulate long bone growth (synergy with growth hormone) and neural maturation, and increase the body’s sensitivity to catecholamines (such as adrenaline) by permissiveness.
Why it is called thyroxine?
The thyroid gland is an important part of the endocrine system, secreting a number of hormones that affect everything from heart health to metabolism. One of those hormones is thyroxine, also known as T4. Because of the many functions that thyroxine impacts, it is considered one of the most important thyroid hormones.
What does T4 do in the body?
Thyroxine (T4) is responsible for your metabolism, mood, and body temperature, among other things. T3, too, is made in the thyroid gland, and it can also be made in other tissues within the body by converting T4 (in a process called deiodination) into T3.
What effects does thyroxine have on the body?
Thyroxine is one of the main hormones secreted from the thyroid follicular cells. Within the body, thyroxine affects the body’s metabolism and has an effect on protein synthesis. It is also important for human growth and development, as it regulates bone growth and aids in the maturation of neurons.
What does thyroxine help regulate?
Thyroxine plays a crucial role in heart and digestive function, metabolism, brain development, bone health, and muscle control . It affects almost all of the body’s systems, which means proper thyroxine levels are vital for health.
What is the action of thyroxine in the cells?
Thyroxine’s principal function is to stimulate the consumption of oxygen and thus the metabolism of all cells and tissues in the body. Thyroxine is formed by the molecular addition of iodine to the amino acid tyrosine while the latter is bound to the protein thyroglobulin.
How does thyroxine stimulate growth?
Thyroxine stimulates oxidative metabolism in cells and increases the oxygen consumption and heat production of most body tissues, with the notable exception of the brain. Thyroxine is also necessary for normal growth, likely by promoting the effects of growth hormone on protein synthesis.