What is sensitisation in biology?
Sensitization. Sensitization is the strengthening of a neurological response to a stimulus due to the response to a secondary stimulus. For example, if a loud sound is suddenly heard, an individual may startle at that sound.
What is sensitization physiology?
Sensitization, also referred to as reverse tolerance, is a phenomenon in which following repeated exposure to the same dose of a particular drug of abuse, a specific behavioral, physiological, or cellular response increases, rather than decreases, over time.
What does sensitized mean in immunology?
Sensitization is a process by which the immune system will produce an antibody, which is a defensive protein, in response to a substance—such as certain foods, pollen, mold, or medications. 2 As such, allergy symptoms develop due to the reaction triggered by the immune system in response to the allergen.
What is the process of sensitization?
Sensitization is a non-associative learning process in which repeated administration of a stimulus results in the progressive amplification of a response. Sensitization often is characterized by an enhancement of response to a whole class of stimuli in addition to the one that is repeated.
What is the process of Sensitisation?
In healthy individuals, when the immune system registers a substance as a threat, B cells, a type of white blood cell, produce antibodies. This is a process known as sensitisation and is part of the normal immune response. In allergic individuals, the immune system misidentifies a harmless substance as a threat.
What do you mean by sensitization?
1 : the action or process of making sensitive or hypersensitive allergic sensitization of the skin. 2 : the process of becoming sensitive or hypersensitive (as to an antigen) also : the resulting state.
What is the sensitization phase?
The sensitization stage is the primary immune response to an antigen, whereas the effector stage is a secondary immune response. In this context, hypersensitivity (HS) is defined as any excessive or abnormal secondary immune response to an antigen.
What is the purpose of sensitization?
The purpose of the sensitization sessions was to stimulate the transition from awareness to information. On the one hand, they attempted to sensitize actors, which was achieved thanks to strategies of information, clarification, comprehension and exposition based on a common referential.
What are sensitized lymphocytes?
Sensitized-lymphoid cells are also obtained after transfer of cells from the spleen, lymph node, or thymus into lethally-irradiated allogeneic recipients.
What is sensitization medical?
Medical Definition of sensitization 1 : the action or process of making sensitive or hypersensitive allergic sensitization of the skin. 2 : the process of becoming sensitive or hypersensitive (as to an antigen) also : the resulting state.
What is sensitized cell?
n. A cell or bacterium that has combined with specific antibody to form a complex capable of reacting with component. A small cell derived by division and differentiation from a lymphocyte.
What does sensitization mean in immunology?
When does sensitization occur in the nervous system?
Sensitization is the process that occurs after neurogenic inflammation when neurons become more responsive to both nociceptive and non-nociceptive stimuli, namely decrease in thresholds of response, increase in magnitude of response, expansion of receptive field, and emergence of spontaneous activity.
What is the definition of sensitization in science?
Sensitization is defined as the enhancement of a behavioral response elicited by a weak stimulus following another, usually noxious stimulus. D. Ruthirago,
What is pain in the presence of sensitization?
In the presence of sensitization, pain and stiffness are experience within normal non-noxious ROM and as severe pain at end-ranges. Under normal circumstances sensitization is a positive protective response to injury. Following injury, the site of damage, as well as its surrounding area, will become hypersensitive to touch, movement or temperature.
What are the antecedent factors for central sensitization?
Antecedent factors can also play a role in the development of central sensitization. The onset of pain is often associated with subsequent development of conditions such as depression, fear-avoidance, anxiety and other stressors.