What is pulmonary thrombolysis?
Catheter-directed thrombolysis (CDT) is one of the newest treatment options for massive and submassive pulmonary embolisms with hemodynamic instability. [1] CDT involves the infusion of a thrombolytic agent intravascularly adjacent to the clot burden through a percutaneous transcatheter.
How does Sonothrombolysis work?
Sonothrombolysis is typically applied to help enhance thrombolytic treatment outcomes. This treatment technique takes advantage of the mechanical bioeffects of ultrasound to aid in the diffusion of thrombolytic drugs into blood clots and to mechanically break up blood clots.
What is ultrasound assisted thrombolysis?
Ultrasound-assisted thrombolysis may be considered as pharmacomechanical thrombolysis and consists of a combination of CDT with a catheter system that employs ultrasound energy. 21. Basic research has demonstrated that ultrasound facilitates the delivery of thrombolytic agents into blood clots.
What is EKOS procedure?
The device, called EKOS is a cutting-edge technology that uses an ultrasound to deliver very low doses of a clot-dissolving drug directly into the clot through a catheter. The result is rapid clearance of the clot while at the same time significantly reducing the risk of bleeding.
What are PE thrombolytics?
Alteplase (rt-PA) is still the most commonly used thrombolytic agent in pulmonary embolism. The approved dose for PTE is infusion of 100 mg in 2 hours. This dose is known to cause major bleeding complications (primarily cerebral hemorrhage), especially in older patients.
What is Percutaneous thrombolysis?
Abstract. Percutaneous thrombectomy (PT) is an established technique for the removal of acute thrombus in occluded arteries, veins and vascular grafts. Percutaneous thrombectomy can be used as an adjunctive treatment to other methods of thrombus removal such as thrombolysis or as sole therapy.
What is catheter-directed thrombolysis?
Catheter-directed thrombolysis is a minimally invasive treatment that dissolves abnormal blood clots in blood vessels to help improve blood flow and prevent damage to tissues and organs.
When do you use thrombolysis?
Most strokes are caused when blood clots move to a blood vessel in the brain and block blood flow to that area. For such strokes (ischemic strokes), thrombolytics can be used to help dissolve the clot quickly. Giving thrombolytics within 3 hours of the first stroke symptoms can help limit stroke damage and disability.
What is percutaneous aspiration thrombectomy?
Percutaneous thrombectomy (PT) is an established technique for the removal of acute thrombus in occluded arteries, veins and vascular grafts. Percutaneous thrombectomy can be used as an adjunctive treatment to other methods of thrombus removal such as thrombolysis or as sole therapy.