What is meropenem antibiotic used for?
Meropenem injection is used to treat skin and abdominal (stomach area) infections caused by bacteria and meningitis (infection of the membranes that surround the brain and spinal cord) in adults and children 3 months of age and older. Meropenem injection is in a class of medications called antibiotics.
What is the difference between meropenem and ertapenem?
In general for these target pathogens, based on MIC90 values, ertapenem has similar potency to meropenem and is slightly more potent than imipenem against Gram-negative pathogens whereas imipenem is slightly more potent against Gram-positive pathogens.
Does meropenem cover MRSA?
Meropenem is active against methicillin-susceptible S. aureus and most strains of methicillin-susceptible coagulase-negative staphylococci. However, as with other carbapenems, meropenem has poor activity against MRSA and methicillin-resistant coagulase-negative staphylococci.
Does meropenem cover for MRSA?
Which cephalosporin covers MRSA?
Ceftaroline is a novel fifth-generation cephalosporin, which exhibits broad-spectrum activity against Gram-positive bacteria, including MRSA and extensively-resistant strains, such as vancomycin-intermediate S. aureus (VISA), heteroresistant VISA (hVISA), and vancomycin-resistant S. aureus (VRSA).
Why meropenem is better than imipenem?
Against Enterobacteriaceae, meropenem is four- to 16-fold more active than imipenem. Meropenem is approximately eightfold more active than imipenem against Haemophilus influenzae and Neisseria gonorrhoeae. B cepacia displays intermediate resistance, and S maltophilia is resistant to both agents.
What does meropenem does not cover?
How is meropenem used in the treatment of MRSA?
KEY POINTS. Meropenem (Merrem) is an injectable carbapenem and beta-lactam antibiotic that interferes with bacterial cell wall synthesis in sensitive organisms. Has activity versus a wide array of organisms, including multi-drug resistant Acinetobacter baumannii, Pseudomonas aeruginosa and Klebsiella pneumoniae DOES NOT cover MRSA or VRE.
What kind of bacteria are killed by meropenem?
MICs of meropenem for selected clinical isolates of bacteria were determined. Killing curves were performed on strains of methicillin-sensitive Staphylococcus aureus, methicillin-resistant Staph. aureus (MRSA), methicillin-resistant Staph, epidermidis, Escherichia coli, Klebsiella spp., Enterobacter …
Are there any evidence based treatments for MRSA?
The Infectious Diseases Society of America (IDSA) has released its first evidence-based guidelines on the treatment of MRSA infections. In addition to common clinical syndromes, the guidelines address treatment with vancomycin, limitations of susceptibility testing, and alternative therapies.
What are the treatment options for MRSA pneumonia?
Treatment options for health care–associated MRSA or community-associated MRSA pneumonia include seven to 21 days of intravenous vancomycin or linezolid, or clindamycin (600 mg orally or intravenously three times per day) if the strain is susceptible.