What is dyslipidemia in type 2 diabetes?
Dyslipidemia, which affects almost 50% of patients with type 2 diabetes, is a cardiovascular risk factor characterized by elevated triglyceride levels, low high-density lipoprotein cholesterol levels, and a preponderance of small, dense, low-density lipoprotein particles.
What does diabetic dyslipidemia mean?
Diabetic dyslipidemia is characterized by elevated fasting and postprandial triglycerides, low HDL-cholesterol, elevated LDL-cholesterol and the predominance of small dense LDL particles. These lipid changes represent the major link between diabetes and the increased cardiovascular risk of diabetic patients.
Is dyslipidemia a complication of diabetes?
Dyslipidemia is one of the risk factors for vascular complications in diabetic patients because it increases free fatty acid flux secondary to insulin resistance and aggravated by increased inflammatory adipokine levels [8].
What is the difference between hyperlipidemia and dyslipidemia?
Hyperlipidemia refers to high levels of LDL or triglycerides. Dyslipidemia can refer to levels that are either higher or lower than the normal range for those blood fats.
Do diabetics have dyslipidemia?
Dyslipidemia is a common feature of diabetes [20]. There is an association between atherosclerotic cardiovascular disease and serum cholesterol and triglyceride levels in both type 1 and type 2 diabetes [21, 22].
WHO criteria dyslipidemia?
LDL cholesterol ≥190 mg/dL. LDL cholesterol ≥160 mg/dL and the presence of two or more cardiovascular risk factors, even after vigorous intervention.
Why is dyslipidemia a risk factor for diabetes?
Dyslipidemia is one of the major risk factors for cardiovascular disease in diabetes mellitus. The characteristic features of diabetic dyslipidemia are a high plasma triglyceride concentration, low HDL cholesterol concentration and increased concentration of small dense LDL-cholesterol particles.
Why do diabetics have dyslipidemia?
Several factors are likely to be responsible for diabetic dyslipidemia: insulin effects on liver apoprotein production, regulation of lipoprotein lipase (LpL), actions of cholesteryl ester transfer protein (CETP), and peripheral actions of insulin on adipose and muscle.
When do ADA guidelines for dyslipidemia come out?
ADA recommendations are released each January. Below is a succinct ACP review of guidelines in screening, treatment goals, lifestyle intervention, and drug approach to dyslipidemia in the setting of diabetes mellitus. LDL-cholesterol is still a main target.
How is dyslipidemia related to type 2 diabetes?
Type 2 diabetes is associated with a two- to fourfold excess risk of cardiovascular disease (CVD). The most common pattern of dyslipidemia in patients with type 2 diabetes patients is elevated triglyceride levels and decreased HDL cholesterol levels.
Is there an Ada standard of care for diabetes?
The ADA also publishes the abridged Standards of Care yearly for primary care providers in its journal, Clinical Diabetes, and offers a convenient Standards of Care app as well as a Standards of Care pocket chart.
When to get a lipid profile for diabetes?
In adults not taking statins, it is reasonable to obtain a lipid profile at the time of diabetes diagnosis, at an initial medical evaluation, and every 5 years thereafter, or more frequently if indicated.