What is clofibrate used for?
Clofibrate is a fibric acid derivative used in the therapy of hypertriglyceridemia and dyslipidemia. Clofibrate therapy is associated with mild and transient serum aminotransferase elevations and with rare instances of acute liver injury.
When should Lopid be discontinued?
Serum concentrations of lipoproteins should be monitored regularly and dosage adjusted to individual requirements. In clinical trials, doses have ranged from 900—1600 mg/day PO. Gemfibrozil should be discontinued if serum lipoprotein concentrations do not improve substantially after 3 months of therapy.
What is the brand name for gemfibrozil?
Gemfibrozil oral tablet is available as a brand-name drug and a generic drug. Brand name: Lopid. Gemfibrozil comes only in the form of a tablet you take by mouth. Gemfibrozil is used to lower triglycerides, a type of fat in your bloodstream.
Is clofibrate a pro drug?
In the body it is converted into 4-chlorophenoxyisobutyric acid (clofibric acid), which is the true hypolipidemic agent. So clofibride, just like clofibrate is a prodrug of clofibric acid.
What are the side effects of LOPID?
Common side effects of Lopid include:
- stomach upset,
- stomach/abdominal pain,
- nausea,
- vomiting,
- diarrhea,
- headache,
- dizziness,
- drowsiness,
Is gemfibrozil bad for your liver?
Gemfibrozil is a fibric acid derivative used in the therapy of hypertriglyceridemia and dyslipidemia. Gemfibrozil therapy is associated with mild and transient serum aminotransferase elevations and with rare instances of acute liver injury.
Is gemfibrozil good for cholesterol?
Gemfibrozil is used along with a proper diet to help lower fats (triglycerides) and raise “good” cholesterol (HDL) in the blood. It may also help to lower “bad” cholesterol (LDL). Gemfibrozil belongs to a group of drugs known as “fibrates.” It works by decreasing the amount of fat produced by the liver.