What causes oral lichenoid reaction?
A lichenoid drug eruption is a reaction to a medication. Some of the types of drugs that may trigger this condition include: anticonvulsants, such as carbamazepine (Tegretol) or phenytoin (Dilantin, Phenytek) antihypertensives, including ACE inhibitors, beta-blockers, methyldopa, and nifedipine (Procardia)
What is oral lichenoid?
Oral lichenoid lesion (OLL) is a chronic inflammatory lesion of the oral mucosa that occurs as an allergic response to dental materials, to use of certain medications, in patients with graft-vs-host disease (GVHD), in patients with systemic diseases, e.g., chronic hepatitis C[1] and patients vaccinated against …
What causes lichenoid?
The exact cause of lichenoid keratosis isn’t known. It may be due to an inflammatory reaction. This happens when your immune system mistakenly attacks the skin. This reaction may be triggered by excess sun or UV light exposure, skin irritation, and some medications.
What is the difference between Lichen Planus and lichenoid reaction?
Oral lichen planus (OLP) and oral lichenoid reaction (OLR) are clinically and histopathologically similar diseases. Whereas OLP is a consequence of T cell mediated autoinflammatory process to a still unknown antigen, OLR might be caused by drugs, dental restorative materials and dental plaque.
How long does a lichenoid reaction last?
Generally, the latent period is 2–3 months (although this can vary for different drugs) and has even been reported to develop after the drug has been ceased.
What drugs cause lichenoid reaction?
Medications commonly reported to trigger a lichenoid drug eruption include:
- Antihypertensives – ACE inhibitors, beta-blockers, nifedipine, methyldopa.
- Diuretics – hydrochlorothiazide, frusemide, spironolactone.
- Non-steroidal anti-inflammatory drugs (NSAIDs)
- Phenothiazine derivatives.
Does Oral Lichen Planus go away?
In most cases, lichen planus will go away within 2 years. If you have symptoms, such as severe itching or sores in your mouth or genital area, treatment can help.
Is lichenoid reaction malignant?
The most important complication of lichenoid reactions is the possibility of malignant transformation. That is why it has been considered a precancerous condition. Although the malignant transformation rate varies widely in the literature, from 0.4 to 6.5 percent, in most studies it does not exceed 1%.
How do you treat an inflamed lichenoid?
How to treat lichenoid dermatitis?
- Discontinuation of medication if a drug is the culprit.
- Steroid creams such as cortisone creams.
- Antibiotics may also be used to help clear your skin of the rash.
- Laser therapy for cases where skin discoloration has occurred.