How does the toxin of Vibrio cholerae cause profuse diarrhea quizlet?
The cholera bacterium Vibrio cholerae produces an enzyme toxin that chemically modifies a G protein involved in regulating salt and water secretion in intestinal cells. An infected person quickly develops profuse diarrhea and if left untreated can soon die from the loss of water and salts.
Which of the following statements best describes the effect of a mutation that knocks out the GTPase activity of Ag protein?
A mutation that knocks out the GTPase activity of a G protein would have what effect on a cell? The G protein would always be active. Which of the following statements describes the events of apoptosis?
Which of the following is the best explanation for the inability of a specific animal cell to reduce the Ca2+ concentration in its cytosol compared with the extracellular fluid?
Bio – ch 11
| Question | Answer |
|---|---|
| 21) Which of the following is the best explanation for the inability of a specific animal cell to reduce the Ca2+ concentration in its cytosol compared with the extracellular fluid? | insufficient ATP levels in the cytoplasm |
Why does testosterone a lipid soluble signaling molecule?
Why does testosterone, a lipid-soluble signaling molecule that crosses the membranes of all cells, affect only target cells? Intracellular receptors for testosterone are present only in target cells. A conformational change in the signal-receptor complex activates an enzyme.
What is the effect of cholera toxin on cAMP in the intestinal cells quizlet?
Cholera toxin activates the adenylate cyclase enzyme in cells of the intestinal mucosa leading to increased levels of intracellular cAMP, and the secretion of H20, Na+, K+, Cl-, and HCO3- into the lumen of the small intestine.
What is the effect of cholera toxin on cAMP in the intestinal cells?
Cholera toxin (CT), a virulence factor elaborated by Vibrio cholerae, is sufficient to induce the severe diarrhea characteristic of cholera. The enzymatic moiety of CT (CtxA) increases cAMP synthesis in intestinal epithelial cells, leading to chloride ion (Cl−) efflux through the CFTR Cl− channel.
Which of the following statements describes a likely effect of a drug designed that inhibits the cellular response to testosterone?
Which of the following statements describes a likely effect of a drug designed that inhibits the cellular response to testosterone? The transcription of certain genes would decrease.
Which of the following statements describes a likely effect of a drug that inhibits testosterone a steroid binding to its receptor in human cells?
Which of the following statements describes a likely effect of a drug that inhibits testosterone binding to its receptor in human cells? The expression of certain genes would increase or decrease.
Which of the following statements would best explain the inability of an animal cell to reduce the Ca2+ concentration in its cytosol?
Which of the following statements best would best explain the inability of an animal cell to reduce the Ca2+ concentration in its cytosol? Insufficient amounts of ATP are present in the cytosol. An inhibitor of which of the following enzymes could be used to block the release of calcium from the endoplasmic reticulum?
What is most likely to happen to an Animalâ s target cells that lack receptors for local regulators?
What is most likely to happen to an animal’s target cells that lack receptors for local regulators? They might not be able to multiply in response to growth factors from nearby cells. Even in the simplest organisms, sexual reproduction required several coordinated responses by cells.
Why does testosterone aldosterone a lipid-soluble signaling molecule that crosses the membranes of all cells affect only target cells?
Lipid-soluble signaling molecules, such as testosterone, cross the membranes of all cells but affect only target cells because: only target cells possess the cytosolic enzymes that transduce the testosterone.
Why does testosterone only affect target cells quizlet?
Testosterone, a lipid-soluble signaling molecule, crosses membranes of cells throughout the body but affects only target cells because: intracellular receptors for testosterone are present only in target cells.
What kind of disease does Vibrio cholerae cause?
Cholera is a well-known disease caused by intestinal infection with the toxin-producing bacteria Vibrio cholerae. This potentially fatal diarrheal disease results in large volumes of watery stool, causing rapid dehydration that can progress to hypovolemic shock and metabolic acidosis.
What causes a large amount of diarrhea during cholera?
Cholera is a bacterial infection of the small intestine that causes a large amount of watery diarrhea. Cholera is caused by the bacteria Vibrio cholerae. These bacteria release a toxin that causes an increased amount of water to be released from cells that line the intestines. This increase in water produces severe diarrhea.
What bacterium causes the disease cholera?
Cholera is caused by the bacterium Vibrio cholerae. These bacteria release a toxin that causes an increased amount of water to be released from cells that line the intestines. This increase in water produces severe diarrhea. People get the infection from eating or drinking food or water that contains the cholera germ.
What are the drug targets for cholera diarrhea?
This review provides an overview of the pathophysiology of cholera diarrhea and discusses emerging drug targets for cholera, which include V. cholerae virulence factors, V. cholerae motility, CT binding to GM1 receptor, CT internalization and intoxication, as well as cAMP metabolism and transport proteins involved in cAMP-activated Cl(-) secretion.