How common is factor 2 mutation?
A change in the prothrombin gene is present in 2-4% (or 1 in 50 to 1 in 25) of Caucasians, and is more common in individuals of European ancestry. In the United States, approximately 0.4% (about 1 in 250) of African Americans also have the mutation.
Is Factor 2 mutation rare?
About one in every 50 white people in Europe and North America has the heterozygous prothrombin gene mutation, making it the second most common inherited clotting disorder.
What is factor 2 blood test?
The factor II assay is a blood test to measure the activity of factor II. Factor II is also known as prothrombin. This is one of the proteins in the body that helps the blood clot.
How is factor 2 diagnosed?
Testing. Diagnosis is made with a prothrombin time (PT) test and an activated partial thromboplastin time (aPTT) test. Levels of prothrombin deficiency can range from 2% to 50% of normal. Patients with levels near or at 50% of normal have little to no bleeding problems.
How is factor 2 treated?
Treatment of factor II deficiency is aimed at restoring circulating factor II to levels sufficient for hemostasis. Levels greater than 30% of normal are usually adequate. Treatment measures include fresh frozen plasma (FFP), prothrombin complex concentrates (PCCs), and vitamin K.
Is Factor 2 dominant or recessive?
Many people with prothrombin-related thrombophilia never develop abnormal blood clots. This condition is caused by a particular genetic variant (written G20210A or 20210G>A) in the F2 gene and is inherited in an autosomal dominant pattern.
How much does MTHFR test cost?
Using Push Health, you can easily request a MTHFR test from a licensed medical provider, get tested at a lab near you, and get results electronically. The total fees are $143.29 and include the lab order, lab fees and an electronic copy of the results.
How is Factor 2 deficiency treated?
What does a protime test for?
The prothrombin time, sometimes referred to as PT or pro time test, is a test to evaluate blood clotting. Prothrombin is a protein produced by your liver. It is one of many factors in your blood that help it to clot appropriately.
How is factor II deficiency treated?