What is Wagner Stickler syndrome?
Wagner syndrome is a rare progressive genetic disorder characterized by mild nearsightedness (myopia), degeneration of the thick, jelly-like fluid (vitreous) that fills the center of the eyes and the thin layer of nerve cells (retina) that lines the back of the eye (vitreoretinal degeneration), and distinctive facial …
What are the different types of Stickler syndrome?
There are five types of Stickler syndrome: Stickler syndrome type I, Stickler syndrome type II, Stickler syndrome type III, Stickler syndrome type IV, and Stickler syndrome type V. Individuals with Stickler syndrome type I tend to have milder hearing loss, nearsightedness, and type 1 membranous vitreous anomaly.
Is Stickler syndrome progressive?
Stickler syndrome is a progressive disorder, so the symptoms are likely to become more severe as your child ages.
What is the prognosis for Stickler syndrome?
Outlook / Prognosis Stickler syndrome has no cure, but it does not affect life expectancy. With ongoing treatment and support, many people with Stickler syndrome live active and fulfilling lives. Prompt diagnosis is important so a doctor can repair abnormalities and help prevent complications.
Is Stickler Syndrome considered a disability?
If you or your dependent(s) are diagnosed with Stickler Syndrome and experience any of these symptoms, you may be eligible for disability benefits from the U.S. Social Security Administration.
Can Stickler Syndrome be detected before birth?
Molecular genetic testing can be used to diagnose Stickler syndrome. A clinical geneticist can discuss this in detail with you and arrange for it, if appropriate. Your doctor may suggest it to confirm a suspected diagnosis or for prenatal diagnosis.
What does Glossoptosis mean?
Definition. Posterior displacement of the tongue into the pharynx, i.e., a tongue that is mislocalised posteriorly. [ from HPO]
How common is Wagner syndrome?
Wegener’s granulomatosis (WG) is not a contagious disease, and there is no evidence to suggest that it is hereditary either. It is a very rare disease, affecting only 1 in every 30,000-50,000 people. About 500 new cases are diagnosed each year. The disease can occur at any age, however, it mostly affects individuals in their 30s and 40s.
Is Stickler syndrome dominant?
Stickler syndrome is an autosomal dominant genetic disorder which means that affected individuals have a 50 percent chance of passing along the syndrome.
What is sticklers disease?
Stickler syndrome is a progressive genetic disease of the connective tissue that causes abnormalities with vision, hearing and skeletal development. The name comes from Dr. G. B. Stickler, who initially described the condition in 1965.