What is the treatment for autoimmune thrombocytopenia?
Medications to treat ITP may include: Steroids. Your doctor will likely start you on an oral corticosteroid, such as prednisone. Once your platelet count is back to a safe level, you can gradually discontinue taking the drug under the direction of your doctor.
Which drug is useful in management of idiopathic thrombocytopenic purpura refractory to prednisone?
Cyclosporin A for the treatment of patients with chronic idiopathic thrombocytopenic purpura refractory to corticosteroids or splenectomy. Br J Haematol. 2001 Jul;114(1):121-5. doi: 10.1046/j.
Can cyclosporine increase platelets?
Cyclosporine therapy also increases spontaneous activation of platelets,23 makes platelets hyperaggregable in response to various agonists,1220212223 and causes increased expression of fibrinogen receptors on their surface membranes.
What is cyclosporine used to treat?
Cyclosporine and cyclosporine (modified) are used with other medications to prevent transplant rejection (attack of the transplanted organ by the immune system of the person who received the organ) in people who have received kidney, liver, and heart transplants.
What autoimmune disease destroys platelets?
Idiopathic thrombocytopenic purpura (ITP) is a rare autoimmune disorder that causes you to have low platelet levels. Platelets are cell fragments that are found in the blood and normally help the blood to clot. In people with ITP, the body produces antibodies that attack and destroy the platelets.
What is the best medicine for ITP?
Since spontaneous remissions are uncommon in adults with ITP, the administration of glucocorticoids is the recommended treatment when necessary. Prednisone (1 mg/kg per day orally) or high-dose dexamethasone (HDD), 40 mg/day orally for 4 days, repeated every 14–28 days as needed, are the regimens most commonly used.
How do you treat thrombocytopenia ash?
In adults with newly diagnosed ITP, the ASH guideline panel recommends against a prolonged course (>6 weeks) of prednisone in favor of a short course (≤6 weeks) and suggests either prednisone (0.5 – 2.0 mg/kg/day) or dexamethasone (40 mg/day for 4 days) as the type of corticosteroid for initial therapy1 .