What is the AST ALT ratio for cirrhosis?
Among 100 patients with chronic type B hepatitis, the mean AST/ALT ratio was 0.59 in those without cirrhosis and 1.02 in those with cirrhosis. Furthermore, the AST/ALT ratio often rose to greater than 1.0 when cirrhosis first became manifest.
Is it OK if AST is higher than ALT?
An AST/ALT ratio equal to one (where the ALT is equal to the AST) may be a sign of acute viral hepatitis or drug-related liver toxicity. An AST/ALT ratio higher than one (where the AST is higher than ALT) means you may have cirrhosis.
How accurate is the AST ALT ratio?
Combined assessment of the AST/ALT ratio and/or PLT obtained 97.0% positive predictive value and 97.9% negative predictive value for the diagnosis of cirrhosis. The AST/ALT ratio had 81.3% sensitivity and 55.3% specificity in identifying cirrhotic patients who died within 1-year of follow-up.
What is the formula to determine AST ALT ratio?
ASTALT_r = AST:ALT Ratio (S, ratio) AST = Aspartate aminotransferase (S, U/L) ALT = Alanine aminotransferase (S, U/L) *Ratio >2.0 suggests alcoholic liver disease.
What does high AST and high ALT mean?
ALT stands for alanine aminotransferase, which is another type of liver enzyme. If you have high levels of AST and/or ALT, it may mean that you have some type of liver damage. You may also have an AST test part of a series of liver function tests.
What should an ideal AST/ALT ratio be?
The AST:ALT ratio in a healthy individual would be around 1.15. If the ratio is more than 2.0 (up to 6.0), this denotes alcoholic liver disease. And if the ratio is between 1.4 and 2.0, it suggests cirrhosis.
What is a high AST ALT level?
A high AST level often means there is some liver damage, but it is not necessarily caused by hepatitis C. A high AST with a normal ALT may mean that the AST is coming from a different part of the body. It is important to realize that the AST level in most patients with hepatitis C goes up and down.