What is temozolomide used to treat?
Temozolomide is used to treat certain types of brain tumors. Temozolomide is in a class of medications called alkylating agents. It works by slowing or stopping the growth of cancer cells in your body.
What is oral temozolomide?
Descriptions. Temozolomide is used to treat specific types of brain cancer (eg, glioblastoma multiforme, anaplastic astrocytoma) in patients whose tumors have returned or whose tumors have just been diagnosed. It belongs to the group of medicines known as antineoplastics (cancer medicines).
How bad is temozolomide?
Temozolomide interferes with the growth of cancer cells, which are then destroyed by the body. Since the growth of normal body cells may also be affected by temozolomide, other side effects may occur. Some of these may be serious and must be reported to your doctor.
How long can you take temozolomide for?
Temodar is usually the first line of chemotherapy drug used to treat gliomas. As long as you tolerate the chemotherapy well, and MRIs show no evidence of a growing tumor, then you may take Temodar for 12 cycles. It can be used safely for up to 24 cycles.
How do you feel on temozolomide?
What are the side-effects of temozolomide?
- Fatigue. People have reported feeling tired during treatment and for up to 12 months afterwards.
- Nausea and vomiting.
- Constipation.
- Loss of appetite.
- Amenorrhoea (an absence of periods)
- Infection.
Does temozolomide cause hair loss?
Headache Let your doctor know if you have headaches while having treatment with temozolomide. Tiredness and feeling weak You may feel very tired|. It is important to allow yourself plenty of time to rest. Hair loss This is rare, but your hair may thin, or occasionally fall out completely.
Can you eat after taking temozolomide?
TAKING TEMOZOLOMIDE CAPSULES Your shouldn’t eat anything one hour before or one hour after taking the capsules. They should be swallowed whole with a glass of water and should not be opened or chewed. You should take the capsules at the same time each day.
Does temozolomide cause weight gain?
Change in taste. Weight gain. Signs of a common cold. Mouth irritation or mouth sores.
When to discontinue temozolomide 100 mg / m 2?
Permanently discontinue Temozolomide capsules in patients who are unable to tolerate a dose of 100 mg/m 2 per day. When ANC is above 1.5 x 10 9 /L, resume Temozolomide capsules at reduced dose for the next cycle. Unable to tolerate a dose of 100 mg/m 2 per day.
Are there any side effects when taking temozolomide?
Based on findings from animal studies and its mechanism of action, Temozolomide capsules can cause fetal harm when administered to a pregnant woman. Adverse developmental outcomes have been reported in both pregnant patients and pregnant partners of male patients.
How is the best way to take temozolomide?
How to use Temozolomide. Take this medication by mouth as directed by your doctor, usually once a day on a treatment schedule. Swallow the capsules whole with a full glass of water (8 ounces or 240 milliliters). Do not crush, chew, or open the capsules. If you vomit after taking your dose, do not take any more medication.
How many mg of Temozolomide should a 3 year old take?
Safety and effectiveness in pediatric patients have not been established. Temozolomide capsules have been studied in 2 open- label studies in pediatric patients (aged 3-18 years) at a dose of 160 to 200 mg/m2 daily for 5 days every 28 days.