What is dexmedetomidine hcl used for?
Precedex (dexmedetomidine hydrochloride) is an alpha2-adrenergic agonist with sedative properties used for short-term intravenous sedation.
When do you take dexmedetomidine?
Dexmedetomidine is indicated for patients requiring a sedation level not deeper than arousal in response to verbal stimulation [corresponding to Richmond Agitation-Sedation Scale6 (RASS) 0 to −3; Table 1]. It is not suitable for patients requiring deep sedation.
What are the side effects of Dexdomitor?
The adverse effects of dexmedetomidine include hypotension, hypertension, nausea, bradycardia, atrial fibrillation, and hypoxia (22, 28) (Figure 4). Overdose may cause first-degree or second-degree atrioventricular block.
Does Dexdomitor lower blood pressure?
During a continuous infusion of dexmedetomidine (0.2–0.7 µg/kg per hour), patients typically experience a slight decrease in blood pressure, heart rate, and cardiac output. This effect is mediated by sympatholysis, as indicated by the fact that patients taking β-blockers do not experience heart rate slowing.
How is dexmedetomidine given?
Dexmedetomidine is given as an infusion into a vein. A healthcare provider will give you this injection. Dexmedetomidine is given using a continuous infusion device that slowly injects the medicine into the body. This type of infusion keeps the patient sedated around the clock.
How quickly does dexmedetomidine work?
Its onset of action is less than 5 minutes and the peak effect occur within 15 minutes. As the pharmacologic effects of dexmedetomidine can be reversed by the α2-AR antagonist atipamezole,[44] dexmedetomidine provides a titratable form of hypnotic sedation that can be readily reversed.
Is Dexdomitor safe?
IMPORTANT SAFETY INFORMATION: Do not use DEXDOMITOR or DEXDOMITOR 0.1 in dogs or cats, and ANTISEDAN in dogs, with cardiovascular disease, respiratory disorders, liver or kidney diseases, or in conditions of shock, severe debilitation, or stress due to extreme heat, cold or fatigue.
Does Dexdomitor cause vasodilation?
In patients, dexmedetomidine causes a biphasic response after intravenous administration; there is an initial vasoconstriction, followed by delayed vasodilation.
What is another name for dexmedetomidine?
Dexmedetomidine
| Clinical data | |
|---|---|
| Trade names | Precedex, Dexdor, Dexdomitor, Sileo |
| AHFS/Drugs.com | Monograph |
| License data | EU EMA: by INN US DailyMed: Dexmedetomidine |
| Pregnancy category | AU : B1 |
What drug class is dexmedetomidine?
Precedex is a prescription medicine used as a sedative before and/or during surgical and other procedures. Precedex may be used alone or with other medications. Precedex belongs to a class of drugs called Sedatives.