What do transitional epithelial cells in urine mean?
They are called transitional cells, renal tubular cells, and squamous cells. If there are squamous epithelial cells in your urine, it may mean your sample was contaminated. This means that the sample contains cells from the urethra (in men) or the vaginal opening (in women).
What does it mean if epithelial cells are transitional?
Transitional epithelium is a stratified tissue in which the cells are all have a fairly round shape when the organ it lines is not distended (stretched out). The image shows the wall of the urinary bladder in the relaxed state (not distended).
What are squamous epithelial cells in dog urine?
Increased white blood cells (pyuria) can occur due to inflammation, infection, trauma, or cancer. Epithelial Cells: Transitional epithelial cells, shed into the urine from the bladder and proximal urethra, are sometimes seen in urine sediment. In a voided urine sample, squamous epithelial cells may be seen.
How do I read my dog’s urinalysis?
Interpretation of a UP:UC is as follows: <0.5:1 (dogs) and <0.4:1 (cats) is normal, 0.4 or 0.5–1:1 is questionable, and >1:1 is abnormal. With primary renal azotemia, a UP:UC >0.5:1 in dogs and >0.4:1 in cats is considered abnormal.
Are transitional cells in urine normal?
A few transitional cells are present in the urine of healthy persons. Increased num- bers are associated with infection. Large clumps or sheets of these cells may be seen with transitional cell carcinoma. Most often, urothelial cells are seen after urethral or ureteral catheterization.
Why is transitional epithelial tissue important?
Because of its importance in acting as an osmotic barrier between the contents of the urinary tract and the surrounding organs and tissues, transitional epithelium is relatively impermeable to water and salts. This impermeability is due to a highly keratinized cellular membrane synthesized in the Golgi apparatus.
What is the importance of the transitional epithelium in the urinary bladder?
Unlike the mucosa of other hollow organs, the urinary bladder is lined with transitional epithelial tissue that is able to stretch significantly to accommodate large volumes of urine. The transitional epithelium also provides protection to the underlying tissues from acidic or alkaline urine.
What are transitional cells?
A cell that varies in shape depending on whether the tissue is being stretched. Transitional cells may be stretched without breaking apart. They line hollow organs such as the bladder.
What is metabolic disease dogs?
Metabolic diseases are anything that disrupts the process of metabolism. This could be a disease in a specific organ, or it could be a systemic disease that affects the overall health of a pet. Metabolic diseases differ from infectious diseases in that there is no inciting organism that causes it.
What are normal urinalysis results for a dog?
Often, normal dogs have urine specific gravity values rang- ing from 1.018 to 1.025, and values have been noted as high as 1.023 to 1.064 in laboratory dogs. In a recent study of healthy pet dogs, urine specific gravity values ranged from 1.006 to greater than 1.050.
What causes transitional cells in urine?
Risk factors for transitional cell cancer of the renal pelvis and ureter include the following: Having a personal history of bladder cancer. Smoking cigarettes. Taking a lot of certain pain medicines, such as phenacetin.
Is transitional cell carcinoma aggressive?
Transitional Cell Carcinoma: An Aggressive Cancer. Transitional cell carcinoma affects the transitional cells of the urinary system and accounts for an overwhelming majority of bladder cancer diagnoses. This cancer may spread rapidly, affecting other organs and becoming life-threatening in some cases.
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