What causes iris transillumination defects?
Known causes of acquired iris atrophy with or without transillumination of the iris include herpetic iridocyclitis, pigment dispersion syndrome (PDS), pseudoexfoliation syndrome, Fuchs uveitis syndrome, Vogt-Koyanagi-Harada disease, trauma, and acute angle-closure glaucoma.
What is iris transillumination defects?
Definition. Transmission of light through the iris as visualized upon slit lamp examination or infrared iris transillumination videography. The light passes through defects in the pigmentation of the iris. [ from HPO]
What is iris transillumination?
Bilateral acute iris transillumination (BAIT) is a recently defined disease characterized with bilateral acute, severe pigment dispersion of iris and pupil sphincter paralysis.
What is Pseudoexfoliation syndrome?
Pseudoexfoliation syndrome (PXF or PEX) is an age-related systemic syndrome that targets mainly ocular tissues through the gradual deposition of fibrillary white flaky material from the lens, mainly on the lens capsule, ciliary body, zonules, corneal endothelium, iris and pupillary margin.
How do you do iris Transillumination?
Iris transillumination requires an undilated pupil and is created by making an axial light beam shine into the small pupil and reflect off the retina. The beam aperture should match the pupil size or be smaller than the pupil to avoid iris reflections.
How do you perform a Transillumination test?
Transillumination test is done by shining high intensity light through a body area or organ to check for any abnormalities like collection of fluid or air. It is bed side test that can be done by getting room lights dimmed or getting room dark so that the glow of light can be seen easily.
What is aqueous flare?
An aqueous flare is an optical phenomenon based on light scattering within the anterior chamber of the eye. This phenomenon occurs when an inflamed eye is viewed at right angles to a beam of light shined obliquely into the anterior chamber.
What is Synechiae?
Synechiae are adhesions that are formed between adjacent structures within the eye usually as a result of inflammation.
What is iris atrophy?
Essential iris atrophy is a very rare, progressive disorder of the eye characterized by a pupil that is out of place and/or distorted areas of degeneration on the iris (atrophy), and/or holes in the iris. This disorder most frequently affects only one eye (unilateral) and develops slowly over time.
Are there any pathognomonic defects in iris transillumination?
Mid-peripheral iris transillumination defects (ITDs) can be pathognomonic for “classic” PDS and may help differentiate it from other causes of pigment dispersal, especially when other clinical signs are mild, absent, or atypical.
Is there a connection between nystagmus and iris transillumination?
Nystagmus and iris transillumination are present in all family members studied. VEP studies show asymmetric decussation of axons in the chiasm. The peripheral retina may have striking hypopigmentation. OCT reveals hypoplasia of the foveal region. Photophobia is not a significant problem. Visual acuity is mildly to moderately reduced.
When do Transillumination defects occur in IFIS patients?
Transillumination defects may also occur in patients with IFIS or intraoperative iris prolapse, due to stretching of the iris tissue. TIDs have also been reported after blunt trauma, after vitrectomy, and after implantation of IOLs, usually single-piece IOLs in the sulcus,…
Can a diffuse iris transillumination be used in albinism?
Diffuse iris transillumination in albinism. Sectorial iris transillumination in herpes zoster iritis. The feature results from iris vasculitis. Note: the transillumination can also be diffuse if the involvement is extensive. Sectorial iris transillumination in a patient with iris prolapse during phacoemulsification.