What are the long term effects of Xyrem?
Respiratory Depression and Sleep-Disordered Breathing XYREM may impair respiratory drive, especially in patients with compromised respiratory function. In overdoses, life-threatening respiratory depression has been reported.
What does Xywav feel like?
Tremor, muscle spasms, feeling drunk and suicidal thoughts have also been reported. In children, the most common side effects include bedwetting, nausea, headache, vomiting, weight decrease, decreased appetite, and dizziness. Xywav is a controlled substance.
Why do you have to wait 2 hours after eating to take Xyrem?
To wait at least 2 hours after eating before they take their first dose of XYREM, because food reduces the bioavailability of XYREM.
Can Xyrem cause psychosis?
Xyrem is usually well tolerated, but both psychosis and depression are described as possible adverse effects of this drug (6, 24–26).
Is sodium oxybate addictive?
Sodium oxybate can slow or stop your breathing, even at regular doses or if you are also taking stimulant medicine. Use the medicine exactly as directed. Sodium oxybate may be habit-forming. Misuse can cause addiction, overdose, or death.
How many people have died from Xyrem?
As of June 30, the F.D.A. had recorded more than 27,000 “serious adverse events” for patients taking Xyrem or Xywav, including 753 deaths, according to the agency’s public database of such reports.
Why is Xyrem taken at night?
XYREM is taken at night to reduce both excessive daytime sleepiness (EDS) in narcolepsy and cataplexy in narcolepsy during the day. XYREM can cause sleep very quickly. Some people fall asleep within 5 minutes, and most people fall asleep within about 15 minutes.
How long after drinking can you take Xyrem?
You should wait at least 2 hours after eating before you take the first dose. Avoid alcohol during treatment, as it may add to the central nervous system effects of sodium oxybate and increase the risk of serious side effects such as respiratory depression, low blood pressure, fainting, coma, and even death.
Can you build a tolerance to Xyrem?
It’s also possible to build up a tolerance to Xyrem. (With tolerance, you feel like you need to take more and more of the drug to have the same effect over time.) Either of these conditions may lead to misuse of Xyrem. Xyrem is a controlled substance, which means that its use is controlled by the federal government.
Is Xyrem approved for fibromyalgia?
Aug. 20, 2010 — An FDA advisory panel today overwhelmingly rejected the application of Jazz Pharmaceuticals for the approval sodium oxybate (Xyrem) for the treatment of fibromyalgia. The drug is chemically similar to GHB, widely considered a date-rape drug.
Is Xyrem addicting?
Xyrem can slow or stop your breathing, even at regular doses or if you are also taking stimulant medicine. Xyrem may be habit-forming. Misuse can cause addiction, overdose, or death. Keep the medication in a place where others cannot get to it.