What are microspheres in medicine?
Microspheres are defined as spherical microscopic particles that range in size from 1–1,000 µm [16,21]. The definition on the basis of size can sometimes be confusing since spheres with a size of over 1,000 μm are still often called microspheres. Here we will focus on medical microspheres that are composed of polymers.
What are microspheres made of?
Microsphere are made from glass, ceramic, carbon or plastic depending on applications. Solid glass microsphere is manufactured by direct burning of glass powders while hollow glass microspheres is produced by adding blowing agent to glass powder.
How do microspheres work?
In microspheres composed of surface-eroding polymers, drug is released primarily at the surface as the polymer breaks down around it. Erosion of such polymers usually proceeds at a constant velocity [66].
What are microspheres biology?
Microspheres are spherical particles with diameters in the micrometer range. In biological research, microspheres can be used as size standards or for adsorbing macromolecules on their surface. These particles can also be used to facilitate cell sorting experiments and immunoprecipitations.
Who discovered microsphere?
Sidney W. Fox
| Sydney Fox | |
|---|---|
| Born | 24 March 1912 Los Angeles |
| Died | 10 August 1998 (aged 86) Mobile, Alabama |
| Known for | Microspheres |
| Scientific career |
Who invented microsphere?
What are microspheres in biology?
What are the characteristics of microspheres?
Microspheres are solid particles with a matrix-like structure and a diameter in the range of 1–1000µm in which the drug is either dissolved or homogenously dispersed in the biodegradable polymer.
How do you create a microsphere?
Sols of varying glass compositions (such as aluminosilicate) are usually produced by chemical precipitation method and then the microspheres are formed either by spray drying of the sols or via a solvent evaporation process (Todea et al. 2013).