Is CCCA inflammatory?
These data indicate that CCCA is an inflammatory scarring alopecia with unique pathophysiologic features that differentiate it from other lymphocytic scarring processes.
What is follicular Mucinosis?
Follicular mucinosis is a rare cutaneous mucinosis characterized by accumulation of mucin at the external root sheath and sebaceous glands [1]. It manifests clinically as follicular papules distributed on the trunk, proximal limbs, scalp, and face; it may also exist as indurated plaques [2].
Can CCCA be misdiagnosed?
CCCA may often be confused with other diseases such as female pattern hair loss, tinea capitis, or lichen planopilaris, which can lead patients to get misdiagnosed.
How do you treat follicular Mucinosis?
Benign follicular mucinosis is usually treated using potent topical corticosteroids or intralesional corticosteroid injections. A range of oral medications may be used including tetracyclines, retinoids and dapsone, antimalarials and corticosteroids. In resistant cases, superficial x-ray therapy may be used.
Is there a cure for follicular Mucinosis?
There exists no treatment of choice for follicular mucinosis (FM).
What happens to the hair follicle in follicular mucinosis?
In follicular mucinosis, a characteristic change in the root vagina of the hair follicle is observed, in which its cells are converted into a mucinous-mucous mass, which leads to the death of the hair follicle and subsequent alopecia.
Which is rare idiopathic follicular mucinosis or urticaria?
Urticaria-like follicular mucinosis (rare). There is no known way to differentiate idiopathic follicular mucinosis from mycosis fungoides or cutaneous T-cell lymphoma-associated follicular mucinosis with certainty.
Is the REM syndrome the same as follicular mucinosis?
With reticular erythematous mucinosis, mucin deposition and moderate mononuclear infiltration are found predominantly around the vessels and hair follicles. Based on the data of morphological and electron microscopic studies, DV Stevanovic (1980) concluded that plaque follicular mucinosis and REM-syndrome are the same condition.
What kind of lymphoma is follicular mucinosis?
Some investigators propose that follicular mucinosis is in fact a form of mycosis fungoides or cutaneous T-cell lymphoma, with a relatively benign or unpredictable course, while others propose that it may be a cutaneous T-cell lymphoid dyscrasia.