Is Aspergillus Ochraceus harmful?
In humans and animals the consumption of this fungus produces chronic neurotoxic, immunosuppressive, genotoxic, carcinogenic and teratogenic effects. Its airborne spores are one of the potential causes of asthma in children and lung diseases in humans.
Where is Aspergillus Ochraceus found?
Aspergillus species like Aspergillus Ochraceus are normally found in coffee beans, tree nuts and other foods that attract mold. It is important to stop production of this fungus and other similiar fungi in the Aspergillus family as they can have toxic effects on humans after contamination and exposure.
What is that toxin that is produced by Ochraceous?
Aspergillus ochraceus
Ochratoxin A, a Toxic Metabolite produced by Aspergillus ochraceus Wilh. Nature.
How toxic is ochratoxin A?
Ochratoxin A (OA), the most toxic member (LD50 about 20ā25 mg kgā1) and also most commonly found toxin in this group, is a potent nephrotoxin causing kidney damage, including degeneration of the proximal tubule, in many animal species.
Is ochratoxin A BAD FOR YOU?
Carcinogenicity. Ochratoxin A is potentially carcinogenic to humans (Group 2B), and has been shown to be weakly mutagenic, possibly by induction of oxidative DNA damage.
How many species of Aspergillus are there?
There are approximately 180 species of Aspergillus, but fewer than 40 of them are known to cause infections in humans. Aspergillus fumigatus is the most common cause of human Aspergillus infections. Other common species include A. flavus, A.
What causes ochratoxin A?
Ochratoxin A is produced by several species of Aspergillus and Penicillium and is a common food-contaminating mycotoxin. Contamination of food commodities, such as cereals and cereal products, coffee beans, dry vine fruits, wine and grape juice, spices and liquorice, occurs worldwide.
What does ochratoxin A do to humans?
OTA causes nephrotoxicity and renal tumors in a variety of animal species; however, human health effects are less well-characterized. Various studies have linked OTA exposure with the human diseases Balkan endemic nephropathy (BEN) and chronic interstitial nephropathy (CIN), as well as other renal diseases.
What kind of fungus is Aspergillus ochraceus?
Aspergillus ochraceus. A member of the Aspergillus genus (comprising about 200 species of fungus worldwide), Aspergillus ochraceus is a species of mold that is frequently found in grains, soil, and dried food products. This species produces ochratoxin A (OTA), a potent mycotoxin that can cause serious kidney damage.
Can you grow Aspergillus ochraceus on grapes?
While Aspergillus ochraceus and Penicillium verrucosum produce OTA in cereals ( ICMSF, 1996 ), these fungi are not commonly isolated in grapes or on vines.
Where are the new species of Aspergillus found?
microspora (1908) and A. ochraceus var. petaliformis (1957). In 1979 two new species were added to the group ā Aspergillus bridgeri, which was discovered in the soils of southern Wyoming, and Aspergillus campestris, first found in North Dakota.
Is there a cure for Aspergillus ochraceus in dogs?
But the dog was treated with oral itraconazole and topical miconazole, which cured the dog after three weeks of medication. In a study, to test the toxicity of OTA in rats, a different dietary dose of OTA was administered to male Fischer rats.