How long should cats be on cisapride?
Cisapride is usually given at least 30 minutes before feeding. Cisapride does not cure the condition for which it is given. Treatment is generally continued for the life of the animal.
What does cisapride do for cats?
Cisapride (brand names: Prepulsid®, Propulsid®) is a medication used to enhance the movement of the gastrointestinal (GI) system to treat conditions such as stasis, reflux, and constipation/megacolon (in cats).
How much cisapride can you give a cat?
Dosage recommendations based on the pharmacokinetics in healthy cats is 1.5 mg/kg orally every 12 hours. Prior to the use of cisapride, an intestinal obstruction should be ruled out because of its strong prokinetic effects. Side effects reported in humans are cramping and diarrhea.
Will cisapride help a constipated cat?
Cisapride is used in cats to manage chronic constipation and megacolon. Work in humans has shown that cisapride is better absorbed when given with food. In small-animal practice it usually is recommended that cisapride be given orally 15 minutes before feeding.
What do you feed a cat with megacolon?
A couple of teaspoons of psyllium, canned pumpkin, or wheat bran can be added to a cat’s regular food to increase the fiber content. Whichever diet works best, it is very important for the cat to remain well-hydrated so stool in the colon stays soft.
How do you prevent megacolon in cats?
Prevention of megacolon can be difficult. The underlying cause must be eliminated, if possible. Some cats prone to constipation may benefit from high fiber diet. Other cats perform better on a highly digestible “low residue” formula.
Is cisapride a laxative?
The effects of cisapride partly outlasted active medication by at least four weeks. It is concluded that cisapride improves bowel habits in patients with idiopathic constipation and reduces laxative consumption.
What type of laxative is cisapride?
Cisapride is a gastroprokinetic agent, a drug that increases motility in the upper gastrointestinal tract. It acts directly as a serotonin 5-HT4 receptor agonist and indirectly as a parasympathomimetic. Stimulation of the serotonin receptors increases acetylcholine release in the enteric nervous system.