Can you eat grapefruit while taking nifedipine?
Do not eat grapefruit or drink grapefruit juice. This is because grapefruit can make the side effects of nifedipine worse. Otherwise, you can eat and drink normally while taking nifedipine. Eating well can help if you have high blood pressure or heart failure.
How does grapefruit juice effect nifedipine?
Grapefruit juice is known to increase the oral bioavailability of dihydropyridine calcium channel blockers, including nifedipine, by reducing presystemic clearance.
How does grapefruit interact with diltiazem?
Interactions between your drugs No interactions were found between diltiazem and grapefruit. This does not necessarily mean no interactions exist. Always consult your healthcare provider.
What herbs interact with nifedipine?
John’s Wort: St. John’s Wort can alter the blood level of nifedipine and should therefore be avoided with it. Tobacco: Cigarette smoking will decrease the effectiveness of the drug in conditions like angina.
Why does grapefruit interact with medications?
Many drugs are broken down (metabolized) with the help of a vital enzyme called CYP3A4 in the small intestine. Grapefruit juice can block the action of intestinal CYP3A4, so instead of being metabolized, more of the drug enters the blood and stays in the body longer.
What are the risks of taking nifedipine?
Commonly reported side effects of nifedipine include: dizziness, peripheral edema, lower extremity edema, flushing, and flushing sensation. Other side effects include: acute myocardial infarction, muscle cramps, tremor, cough, dyspnea, hypotension, and wheezing. See below for a comprehensive list of adverse effects.
Can you take nifedipine medication while grapefruits?
Grapefruits and grapefruit juice may increase the effects of nifedipine by increasing the amount of this medicine in your body. You should not eat grapefruit or drink grapefruit juice while you taking this medicine. Do not take other medicines unless they have been discussed with your doctor.
What could possibly be bad about grapefruit?
Grapefruit can be a healthy snack, but you need to be aware of how it affects your digestion right before bed. However, this yummy fruit is acidic, and eating grapefruit at night could exacerbate heartburn for some people, which is often worse when lying down.
How does grapefruit interact with antibiotics?
Eating grapefruit or drinking grapefruit juice can affect antibiotic metabolism for up to 72 hours. The effect on your medications is worst when the juice or fruit is taken with the medicine or up to 4 hours before you take your dose.