Can MGUS cause skin problems?
Symptoms. People with monoclonal gammopathy generally don’t experience signs or symptoms. Some people may experience a rash or nerve problems, such as numbness or tingling. MGUS is usually detected by chance when you have a blood test for another condition.
Does multiple myeloma cause bruising?
Some people with multiple myeloma have bruising and unusual bleeding (haemorrhage), such as frequent nosebleeds, bleeding gums and heavy periods. This is because the cancer cells in your bone marrow can stop blood-clotting cells called platelets from being made.
Can MGUS cause inflammation?
Inflammation in the setting of autoimmunity may serve as a trigger for MGUS and MM. In addition, a common genetic susceptibility for developing both an autoimmune disease and MM/MGUS might also exist. Autoimmune hematologic and rheumatologic diseases may pose important clinical problems for the MM patients.
Does MGUS cause itchy skin?
Brief Summary: Pruritus is most often secondary to dermatitis but can also occur without skin lesions, it is called pruritus sine materia….Frequency and Characteristics of Pruritus in Patients With Monoclonal Gammopathy (PRURIGAMMA)
| Study Type : | Observational |
| Actual Enrollment : | 281 participants |
What can MGUS lead to?
Light chain MGUS (LC-MGUS). The diseases triggered by MGUS may cause bone fractures, blood clots, and kidney problems over time. These complications can make managing the condition and treating any associated diseases more challenging.
Does MGUS cause neuropathy?
In order to understand the epidemiology of monoclonal gammopathy associated peripheral neuropathy, one needs to appreciate that MGUS is relatively common in the general population, and that the mere presence of an M protein in a patient with neuropathy does not mean that a causal relationship exists.
Does MGUS cause hip pain?
There is a small risk of MGUS developing into a cancer, such as myeloma or lymphoma. If this happens, it can cause certain symptoms. Always contact your doctor if you have any of these symptoms: new or constant bone pain (such as in the back, ribs, hip or pelvis)