Can isoniazid cause pancreatitis?
Isoniazid and rifampicin have been used for several decades in the treatment of pulmonary tuberculosis. It has long been known that both of these drugs can lead to acute pancreatitis, and the first reports of this druginduced pancreatitis appeared in 1973 for rifampicin [5] and in 1994 for isoniazid [6].
Which drug causes acute pancreatitis most frequently?
Drugs definitely associated with acute pancreatitis include the following:
- Azathioprine.
- Sulfonamides.
- Sulindac.
- Tetracycline.
- Valproic acid,
- Didanosine.
- Methyldopa.
- Estrogens.
What medications can cause chronic pancreatitis?
Medicines That Can Cause Pancreatitis
- Antibiotics.
- Medicines that suppress the immune system.
- Medicines used to treat high blood pressure.
- Aminosalicylates.
- Diuretics.
- Corticosteroids.
- Estrogen.
- Medicines used to treat diabetes.
Can drugs cause chronic pancreatitis?
Results: Class I medications (medications implicated in greater than 20 reported cases of acute pancreatitis with at least one documented case following reexposure): didanosine, asparaginase, azathioprine, valproic acid, pentavalent antimonials, pentamidine, mercaptopurine, mesalamine, estrogen preparations, opiates.
Does azithromycin cause pancreatitis?
This regulatory update covers a new warning on azithromycin about abnormal changes in the electrical activity of the heart, and a possible increased risk of pancreatitis and precancerous findings from incretin mimetic drugs.
Why does azathioprine cause pancreatitis?
We hypothesize that azathioprine in the presence of a pre-existing cofactor is more prone to cause pancreatitis and patients with autoimmune pancreatitis have this predisposition with altered pancreatic parenchyma. Thus the second hit in the form of azathioprine could have triggered a severe pancreatitis.
Can statins cause pancreatitis?
These data showed that pancreatitis can occur at both high and low doses, with 12 cases developing pancreatitis at less than the dose equivalent of simvastatin 20 mg daily. Statin-induced pancreatitis can occur at any time but seems to be very uncommon early on and more likely to occur after many months of therapy.
Can azathioprine cause pancreatitis?
Background: Azathioprine is widely used in Crohn’s disease. A major drawback is the occurrence of side-effects, especially acute pancreatitis. Acute pancreatitis is rarely seen when azathioprine is used for other diseases than Crohn’s disease.
Can mesalamine cause pancreatitis?
Acute pancreatitis is a known, although rare, complication of mesalamine treatment. This complication typically appears within the first days or weeks after initiation of therapy. We describe two cases of acute pancreatitis that occurred after long term mesalamine therapy for ulcerative colitis.
Can Humira cause pancreatitis?
With regards to gastrointestinal side effects, adalimumab is well known to cause hepatitis B virus reactivation. However, reports on hypertriglyceridemia and acute pancreatitis are sparse.
Can azithromycin treat pancreatitis?
Azithromycin does not improve disease severity in acute experimental pancreatitis.