Can galantamine and donepezil be taken together?

Can galantamine and donepezil be taken together?

The combination therapy of donepezil plus memantine was better for apathy in older AD patients, and galantamine plus memantine was better for cognitive functions. Conclusions: The addition of memantine stabilized cognitive scores for 6 months and affective scores for 12 months in the donepezil subgroup.

Is Aricept the same as galantamine?

Are Aricept and Razadyne the Same Thing? Aricept (donepezil hydrochloride) and Razadyne ER (galantamine hydrobromide) are cholinesterase inhibitors used to reduce symptoms of mild to moderate dementia like that found in patients with Alzheimer’s disease.

What is an alternative to donepezil?

Galantamine (Razadyne) Galantamine works just as well as donepezil and rivastigmine at controlling symptoms of AD. However, folks with kidney impairment or liver disease should not take galantamine. Galantamine comes in immediate-release and extended-release versions.

What is the difference between donepezil and rivastigmine?

A primary difference between donepezil and rivastigmine is that whereas donepezil is specific for inhibiting AChE, rivastigmine is known to inhibit both AChE and BChE.

Is galantamine the same as memantine?

Galantamine is an acetylcholinesterase inhibitor that is also a positive allosteric modulator at the α4β2 and α7nACh receptors. Memantine is an N-methyl-d-aspartate receptor modulator/agonist.

Can you take Exelon and Aricept together?

If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs.

What are the side effects of galantamine?

Galantamine may cause side effects. Tell your doctor if any of these symptoms are severe or do not go away:

  • nausea.
  • vomiting.
  • diarrhea.
  • loss of appetite.
  • stomach pain.
  • heartburn.
  • weight loss.
  • extreme tiredness.

Which is better for you galantamine or donepezil?

Results are conflicting; two studies suggest no differences in efficacy between compared drugs, while one study found donepezil to be more efficacious than galantamine, and one study found rivastigmine to be more efficacious than donepezil.

What are the side effects of rivastigmine and donepezil?

The most common adverse events reported in trials were nausea, vomiting, diarrhea, dizziness, and weight loss. Across studies, the frequency in which these events were reported was generally lowest for donepezil and highest for rivastigmine.

How much Galantamine can I take in 4 weeks?

Donepezil (5 mg/day for 4 weeks increased to 10 mg/day for 8 weeks); galantamine (4 mg twice daily for 4 weeks, increased to 8 mg twice daily for four weeks, then 12 mg twice daily for 4 weeks).