What does milrinone do for the heart?
Milrinone is a vasodilator that works by relaxing the muscles in your blood vessels to help them dilate (widen). This lowers blood pressure and allows blood to flow more easily through your veins and arteries. Milrinone is used as a short-term treatment for life-threatening heart failure.
How long can you stay on milrinone?
Fifty-one patients successfully began β-blocker therapy while on intravenous milrinone. Oral medical therapy was maximized when possible. The mean duration of milrinone treatment in this combination-treatment group was 269 days (range, 14–1,026 days). Functional class improved from IV to II–III with milrinone therapy.
Is primacor an Inotrope?
PRIMACOR is a positive inotrope and vasodilator, with little chronotropic activity different in structure and mode of action from either the digitalis glycosides or catecholamines.
What type of drug is primacor?
Primacor, brand of milrinone lactate injection, is a member of a class of bipyridine inotropic/vasodilator agents with phosphodiesterase inhibitor activity, distinct from digitalis glycosides or catecholamines.
Why does milrinone cause arrhythmias?
Milrinone can cause tachycardia, partly because of its vasodilatory effects and partly perhaps by a direct effect on the heart. A 74-year-old man had a tachycardia of 145/minute during infusion of milrinone after an operation for repair of an abdominal aortic aneurysm [19].
Can you drive while taking milrinone?
Milrinone can also cause changes in blood pressure, which can cause dizziness or fainting. Do not drive or operate heavy machinery until you know how milrinone affects you.
Is milrinone a po?
Milrinone, commonly known and marketed under the brand name Primacor, is a pulmonary vasodilator used in patients who have heart failure. It is a phosphodiesterase 3 inhibitor that works to increase the heart’s contractility and decrease pulmonary vascular resistance.
Who makes primacor?
As part of its bid to get its merger with DuPont past antitrust regulators, Dow Chemical has agreed to sell its Primacor ethylene acrylic acid (EAA) copolymers business to South Korea’s SK Global Chemical for $370 million.
What is primacor used to treat?
This medication is used for the short-term treatment of heart failure. It works by making your heart beat stronger and by relaxing certain blood vessels so that the amount of blood that is pumped from the heart is increased.