What is quadrupole mass spectrometer used for?
Quadrupole mass analyzers are often used for targeted, quantitative applications and can be used either to measure one or a few given ions in a mixture, or to scan across a range of m/z values. Depending on the configuration, they can facilitate both MS and MS/MS applications.
What is the best mass spectrometer?
Buyers’ Guide: Best Buys for Mass Spectroscopy
- Thermo Scientific™ iCAP™ TQ ICP-MS. Delivering research-level trace elemental analysis, combined with routine ease-…
- rapifleX MALDI-TOF/TOF System.
- timsTOF™ LCMS System.
- Pegasus BT 4D GCxGC Time-of-Flight Mass Spectrometer.
How does quadrupole mass analyzer separate molecular ions?
1 Quadrupole Mass Analyzers. This type of mass analyzer separates ions based on the stability of their flight trajectories through an oscillating electric field in the quadrupole. The field is generated when a radio frequency (RF) voltage is applied between one pair of opposing rods within the quadrupole.
What are some advantages of using a mass spectrometer versus a UV VIS detector when analyzing complex samples?
Mass detection adds a new dimension to the analytical signal, namely the mass to charge ratio (i.e. the molecular weight of the analyte). Combining UV-detection with mass detection helps users come to a more precise conclusion and informs better decision making.
What are the advantages of mass spectrometry based proteomics?
Accurate mass measurements greatly facilitate detailed analysis of intact proteins (and top-down proteomics), as a small mass difference can distinguish between different molecular species.
How does a quadrupole mass spectrometer work?
A quadrupole mass analyzer consists of a set of four conducting rods arranged in parallel, with a space in the middle; the opposing pairs of rods are electrically connected to each other. The field is generated when a radio frequency (RF) voltage is applied between one pair of opposing rods within the quadrupole.