What is Basaloid carcinoma?
Basaloid squamous cell carcinoma (BSCC) is a rare and aggressive variant of oral squamous cell carcinoma with a predilection for the tongue and in other locations, such as floor of the mouth, palate, retromolar trigone, and gingival mucosa.
Which is the commonest histologic type of breast carcinoma?
The two most common histologic types of invasive breast cancer are ductal and lobular carcinomas, accounting for approximately 75 and 15% of all cases in the US, respectively (Li et al, 2003a).
What is a Basaloid cell?
The common feature of nearly all tumours, at least focally, is the presence of (basaloid) cells with small round, oval or elongated nuclei with condensed chromatin and scant cytoplasm. At the edge of tumour islands, cells have a tendency to align perpendicularly to the stromal margin (peripheral palisading).
What is Basaloid keratinocytes?
Basal cell carcinoma is a superficial, slowly growing papule or nodule that derives from certain epidermal cells. Basal cell carcinomas arise from keratinocytes near the basal layer, which are sometimes called basaloid keratinocytes. Metastasis is rare, but local growth can be highly destructive.
What is histologic grade2?
Grade 2: The cells and tissue are somewhat abnormal and are called moderately differentiated. These are intermediate grade tumors. Grade 3: Cancer cells and tissue look very abnormal. These cancers are considered poorly differentiated, since they no longer have an architectural structure or pattern.
What does neoplasm of breast mean?
Definition: Tumors or cancer of the human BREAST. Synonym(s): Breast Cancer / Breast Tumors / Cancer of Breast / Cancer of the Breast /
How many cases of Basaloid carcinoma of the breast?
In this article, we present 9 cases of breast cancer showing overall/predominant basaloid morphology. Patients’ ages ranged from 47 to 75 years (mean, 61.4 years). Surgical treatment included mastectomy or quadrant excision with or without axillary dissection.
What are the characteristics of basal like breast cancer?
Abstract Basal-like breast cancer (BLBC) occurs mainly in young patients. It is characterized by an aggressive clinical outcome, presence of distant metastases, particularly within the first five years of the disease, bad prognosis and relatively high mortality.
What kind of cancer is found in the mammary gland?
The term “breast cancer” refers to a heterogeneous group of tumors developing within the mammary gland and mostly deriving from the epithelium lining the ducts or lobules. They can be divided into two groups: pre-invasive carcinomas in situand invasive carcinomas. The basic method used in diagnosis of breast cancer is histopathological assessment.
What are the characteristics of BRCA1 breast cancer?
Breast cancer in young women with a BRCA1 mutation is characterized by high histological grade and triple-negative phenotype, which is associated with considerably worse prognosis [3].