Does pilocarpine affect blood pressure?
Pilocarpine strongly increases arterial pressure which activates baroreceptors, thereby enhancing the activity of NTS and CVLM neurons, before the release of inhibitory signals in the RVLM trying to reduce sympathetic activation.
What are the side effects of salagen?
Sweating, nausea, runny nose, chills, flushing, frequent urge to urinate, dizziness, weakness, diarrhea, and blurred vision may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. This medication may cause an increase in tears.
Is salagen safe to take?
Salagen may cause blurred vision, especially at night or in low light. Be careful if you drive or do anything that requires you to be able to see clearly. Avoid becoming overheated during exercise and in hot weather. Salagen can increase sweating and you may be more prone to dehydration.
Who should not take pilocarpine?
Before taking pilocarpine, Your doctor may need to change the doses of your medications or monitor you carefully for side effects. tell your doctor if you have asthma, acute iritis (uveitis; swelling and irritation inside the eye), or glaucoma (an eye disease). Your doctor may tell you not to take pilocarpine.
Does pilocarpine decrease heart rate?
Acetylcholine and Pilocarpine slowed the heart rate when they were applied. Conversely, the addition of Epinephrine and Atropine + Acetylcholine increased the heart rate.
What is the generic name for salagen?
Pilocarpine (Salagen) is a cholinergic agonist, meaning it activates cholinergic receptors in your body. This causes your saliva glands to make more saliva so that your mouth is less dry.
What is the generic for Salagen?
What is Salagen 5 mg?
Salagen film-coated tablets are white, round biconvex tablets, marked “SAL” on one side and “5” on the other side. Alleviation of symptoms of salivary gland hypofunction in patients with severe xerostomia following irradiation for head and neck cancer.
Which heart condition s could be treated with pilocarpine?
glaucoma. heart disease. liver disease. lung or breathing disease, like asthma.
What happens to the heart rate after treatment with pilocarpine?
Pilocarpine did decrease the heart rate.
Are there any side effects to taking Salagen?
Tell your doctor if you have unlikely but serious side effects of Salagen including: slow or fast heartbeat, shakiness (tremor), fainting, lung problems (such as increased wheezing/cough/phlegm), mental/mood changes (such as confusion, agitation), or severe stomach or abdominal pain.
Is it safe to take Salagen during pregnancy?
The safety of oral Salagen during pregnancy has not been evaluated. The physician and patient need to weigh the benefits and the unknown risk to the fetus before using Salagen during pregnancy. It is unknown if Salagen is secreted in human breast milk in amounts large enough to affect the nursing infant.
How is Salagen used to treat dry mouth?
Salagen (pilocarpine hydrochloride) is a cholinergic agonistthat increases salivasecretion in the mouth used in the treatment of dry mouth. Salagen is available in genericform.
How often should I take Salagen for head and neck cancer?
The starting dose of Salagen in patients with moderate hepatic impairment is 5 mg twice daily, and then adjusted based on response and tolerability. The recommended initial dose for head and neck cancer patients is 5 mg three times a day. The recommended dose for Sjogren’s Syndrome is 5 mg four times a day.