What kind of vaccine is the Ebola vaccine?
The Ebola virus vaccine ERVEBO is a replication-competent, live, attenuated recombinant vesicular stomatitis virus (rVSV) vaccine manufactured by Merck.
Is Ebola vaccine an mRNA vaccine?
mRNA technology is new, but not unknown. It has been studied for more than a decade and mRNA vaccines have been studied in early stage clinical trials for other diseases such as influenza, Ebola, Zika, and rabies.
What was the first vaccine for Ebola?
The U.S. Food and Drug Administration announced today the approval of Ervebo, the first FDA-approved vaccine for the prevention of Ebola virus disease (EVD), caused by Zaire ebolavirus in individuals 18 years of age and older.
What is the description of Ebola?
Ebola is a virus that causes problems with how your blood clots. It is known as a hemorrhagic fever virus, because the clotting problems lead to internal bleeding, as blood leaks from small blood vessels in your body. The virus also causes inflammation and tissue damage.
What is the purpose of testing an Ebola vaccine in clinical trials?
Brief Summary: This study will test the safety of an experimental vaccine developed to protect against Ebola virus infection and to determine if the vaccine induces an immune response to the virus.
What are the side effects of Ebola vaccine?
Side Effects of Ebola Vaccine For all 3 vaccines, the most common side effects are pain and swelling at the injection site, muscle and joint pain, headache, and tiredness. For rVSV-ZEBOV, other common side effects are redness at the injection site, feverishness, nausea, joint pain, rash, and abnormal sweating.
How does the mRNA vaccine work?
mRNA vaccines teach our cells how to make a protein—or even just a piece of a protein—that triggers an immune response inside our bodies. The benefit of mRNA vaccines, like all vaccines, is those vaccinated gain protection without ever having to risk the serious consequences of getting sick with COVID-19.
How is Ebola virus diagnosis?
Ebola virus can be detected in blood after onset of symptoms. It may take up to three days after symptoms start for the virus to reach detectable levels. Polymerase chain reaction (PCR) is one of the most commonly used diagnostic methods because of its ability to detect low levels of Ebola virus.
What does Ebola virus look like?
Under an electron microscope, it looks like a harmless shepherd’s crook or a scheerio with a long tail, but it can decimate the human immune system in a matter of days and cause death within three weeks. Rare, but deadly, Ebola is a filovirus, one of four distinct families of hemorrhagic fever viruses.