What is Lentiginous junctional nevus with severe atypia?
Atypical lentiginous nevus (of the elderly) is a peculiar form of dysplastic nevus. Clinically, this condition can resemble malignant melanoma and histologically, it has a lentiginous pattern with variable degrees of atypia and an absence of dermal nests.
What does Lentiginous compound melanocytic nevus mean?
Lentiginous melanocytic naevus. Specialty. Dermatology. A melanocytic nevus (also known as nevocytic nevus, nevus-cell nevus and commonly as a mole) is a type of melanocytic tumor that contains nevus cells.
What does severe cytologic atypia mean?
Severe cytologic atypia is defined as enlarged, spindle- and epithelioid-shaped melanocytes with hyperchromatic nuclei of melanocytes that are typically larger than basal keratinocytes (2 times or greater than the nuclei of basal keratinocytes), with distinct nucleoli.
What is a lentiginous nevus?
Background: Atypical lentiginous nevus (of the elderly) is a peculiar form of dysplastic nevus. Clinically, this condition can resemble malignant melanoma and histologically, it has a lentiginous pattern with variable degrees of atypia and an absence of dermal nests.
Can a compound nevus turn into melanoma?
Yes — but most dysplastic nevi do not turn into melanoma. Most types of atypical moles remain stable over time. Patients with five or more dysplastic nevi are 10 times more likely to develop melanoma than individuals with no atypical moles.
Can compound nevus turn into melanoma?
Is acral lentiginous melanoma painful?
Acral lentiginous melanoma may be painful if it reaches advanced stages in certain areas of your body. If lesions are found on the sole of your foot, the growths may thicken as the cancer progresses and may cause walking to be painful.
What does a severely atypical mole mean?
Atypical moles, also known as dysplastic nevi, are unusual-looking moles that have irregular features under the microscope. Though benign, they are worth more of your attention because individuals with atypical moles are at increased risk for melanoma, a dangerous skin cancer.
What is severe dysplastic nevus?
A severely dysplastic nevus is indistinguishable from early melanoma. Very often these lesions show considerable irregularity of edge and irregularly irregular colour. The differentiation between a moderate and severely dysplastic nevus is one of degree. Mildly dysplastic nevi can be observed.
How common is acral lentiginous melanoma?
Acral lentiginous melanoma accounts for 29-72% of melanoma in dark-skinned individuals but less than 1% of melanoma in fair-skinned people, as they are prone to more common sun-induced types of melanoma such as superficial spreading melanoma and lentigo maligna melanoma.
Is atypical nevi cancerous?
About 1 in 10 people develop atypical moles during their lifetime. These moles are not cancerous, and need not be removed if they are not changing. Instead, atypical moles can be a sign of an increased risk for melanoma skin cancer.
Is melanocytic nevus malignant?
Although melanocytic nevi are examples of what are called benign neoplasms, or non-cancerous growths, they have the potential to become malignant, or cancerous. A congenital melanocytic nevus carries a higher risk of melanoma development.
What is a junctional nevus?
A junctional nevus is a mole found in the junction (border) between the epidermis and dermis layers of the skin.
What is severe atypia?
Severe atypia: nuclear enlargement to two times or greater the size of the nuclei of the keratinocytes of the stratum spinosum, prominent nucleoli, abundant granular to dusty (due to fine melanin granules) cytoplasm.