Is zafirlukast a generic?
Accolate is the brand name for zafirlukast. Zafirlukast is available in generic form.
Does zafirlukast cause weight gain?
Weight gain is not a common side effect of zafirlukast (Accolate). Sometimes, people might have stomach issues, like diarrhea or nausea, when they start this medication, but they typically don’t gain weight.
Is zafirlukast an anti inflammatory?
Zafirlukast also exhibited evidence of an anti-inflammatory effect in the lung in preliminary studies involving segmental antigen challenge. The results from these clinical trials demonstrate that zafirlukast is effective and safe for the prophylactic treatment of asthma.
Can you stop Singulair suddenly?
As far as long-term Singulair side effects, the side effects you might have from Singulair don’t change much even with longer treatment. Stopping Singulair suddenly typically doesn’t cause withdrawal symptoms that can make your asthma worse. But to be on the safe side, talk to your doctor before stopping.
Is zafirlukast a rescue or control?
Regular use of this medication can help control your asthma, improve your ability to exercise, and decrease the number of times you need to use your rescue inhaler. This medication works by blocking the activity of natural substances (leukotrienes) that may cause or worsen asthma.
Do I take zafirlukast with food?
Food may change the amount of zafirlukast that is absorbed. It should be taken on an empty stomach, 1 hour before or 2 hours after a meal. To work properly, zafirlukast must be taken every day at regularly spaced times, even if your asthma seems better.
How long does it take for zafirlukast to work?
It may take 1 to 2 weeks before you feel the full benefit of this medication. Inform your doctor if your condition (e.g., asthma symptoms, number of times you use your rescue inhaler) persists or worsens.
How to report side effects of zafirlukast twice daily?
You may report side effects to FDA at 1-800-FDA-1088. -A dose of 20 mg twice daily was not associated with an increase in the overall incidence of adverse events or withdrawals in elderly patients. Less than 5 years: The safety and effectiveness has not been established.
What are the inactive ingredients in zafirlukast tablets?
Zafirlukast is supplied as 10 and 20 mg tablets for oral administration. Inactive Ingredients: Film-coated tablets containing croscarmellose sodium, lactose, magnesium stearate, microcrystalline cellulose, povidone, hypromellose, and titanium dioxide.
What is the terminal half life of zafirlukast?
In the pivotal bioequivalence study, the mean terminal half-life of Zafirlukast is approximately 10 hours in both normal adult subjects and patients with asthma. In other studies, the mean plasma half-life of Zafirlukast ranged from approximately 8 to 16 hours in both normal subjects and patients with asthma.
What is the steady state volume of zafirlukast?
The apparent steady-state volume of distribution (Vss/F) is approximately 70 L, suggesting moderate distribution into tissues. Studies in rats using radiolabeled Zafirlukast indicate minimal distribution across the blood-brain barrier.