Does Klinefelter increase breast cancer?
Men with Klinefelter syndrome are more likely to get breast cancer than other men. Having this condition can increase the risk anywhere between 20 – 60 times the risk of a man in the general population.
Is gynecomastia a risk factor for breast cancer?
Gynecomastia — enlarged male breast tissue — may slightly increase your risk of breast cancer. But even with gynecomastia, your risk of developing male breast cancer is very small. In most cases, gynecomastia resolves on its own with minimal treatment and little risk of long-term complications.
Can males inherit breast cancer?
About 1 out of 5 men who develop breast cancer has a family history of the disease. These men may have inherited a mutation in the BRCA1 or BRCA2 genes or other genes, such as CHEK2 and PALB2, which can increase their risk for breast cancer.
Can a blood test show breast cancer?
Tests and procedures used to stage breast cancer may include: Blood tests, such as a complete blood count. Mammogram of the other breast to look for signs of cancer.
How can you tell the difference between gynecomastia and cancer?
One of the biggest differentiating factors between a male with breast cancer and a male with gynecomastia is symmetry. For instance, men who have gynecomastia almost always exhibit swelling in both of their breasts. Whereas men who have breast cancer, typically only find a lump or swelling in one of their breasts.
Does gynecomastia mean cancer?
Gynecomastia is not necessarily a sign of cancer, but your doctor may run some tests to rule it out. Swelling of the breasts may happen unevenly, with one becoming larger than the other. You may also have breast tenderness.
What are the first signs of male breast cancer?
Symptoms of breast cancer in men
- a lump in the breast – this is usually hard, painless and does not move around within the breast.
- the nipple turning inwards.
- fluid oozing from the nipple (nipple discharge), which may be streaked with blood.
- a sore or rash around the nipple that does not go away.
What is the number one cause of male breast cancer?
The risk of breast cancer increases as you age. Male breast cancer is most often diagnosed in men in their 60s. Exposure to estrogen. If you take estrogen-related drugs, such as those used for hormone therapy for prostate cancer, your risk of breast cancer is increased.
Is there a link between breast cancer and Klinefelter syndrome?
The age-standardized rate is at about 0.9/100,000 inhabitants. The median age lies between 65 and 70 years. The association between Klinefelter syndrome and breast cancer is based on both cytogenetic analyses in men who had acquired breast cancer [ 11] and epidemiological studies.
How is a diagnosis of Klinefelter syndrome confirmed?
Chromosome analysis. Also called karyotype analysis, this test is used to confirm a diagnosis of Klinefelter syndrome. A blood sample is sent to the lab to check the shape and number of chromosomes.
How to prevent lung cancer in men with Klinefelter syndrome?
Considering the potentially higher risk among men with Klinefelter syndrome the general guidelines for the prevention of lung cancer are especially important [24]: 1 No smoking. 2 Avoidance of passive smoking. 3 Avoidance of occupational exposure. 4 Avoidance of radiation exposure. 5 Physical activity. 6 (more items)
What can be done for boys with Klinefelter syndrome?
In males who develop enlarged breasts, excess breast tissue can be removed by a plastic surgeon, leaving a more typical-looking chest. Speech and physical therapy. These treatments can help boys with Klinefelter syndrome who have problems with speech, language and muscle weakness. Educational evaluation and support.