What is contraindicated when giving propofol?

What is contraindicated when giving propofol?

Propofol is also contraindicated in patients with hypersensitivity to the drug or to any of the components. Propofol emulsions contain soybean oil and egg yolk phospholipid or egg lecithin and thus, should not be used in patients with egg hypersensitivity or soya lecithin hypersensitivity.

What do you monitor propofol with?

During the administration of propofol, patients should be monitored without interruption to assess level of consciousness, and to identify early signs of hypotension, bradycardia, apnea, airway obstruction and/or oxygen desaturation.

What are the complications of propofol?

High-dose propofol infusion for sedation of patients in the intensive care unit can result in rhabdomyolysis, acute renal failure, metabolic acidosis, hyperkalemia, ventricular arrhythmia, hyperthermia, and death. The death of a patient with such complications after lung biopsy is reported.

What is required for administration of propofol when given as an IV drip?

Most patients require an infusion of 25 mcg/kg/min to 75 mcg/kg/min (1.5 mg/kg/h to 4.5 mg/kg/h) or incremental bolus doses of 10 mg or 20 mg. In Elderly, Debilitated, Neurosurgical, or ASA-PS III or IV Patients: Most patients require 80% of the usual adult dose.

How do you titrate propofol drip?

Initiation

1. 0.1-0.15 mg/kg/min IV for 3-5 min; titrate to desired clinical effect; monitor respiratory function; administered as slow infusion or slow injection while monitoring cardiorespiratory function.
2. Slow injection: 0.5 mg/kg administered over 3-5 min; titrate to clinical response.

When should you not use propofol?

Who should not take PROPOFOL?

1. low amount of magnesium in the blood.
2. low amount of potassium in the blood.
3. torsades de pointes, a type of abnormal heart rhythm.
4. prolonged QT interval on EKG.
5. abnormal EKG with QT changes from birth.
6. hardening of the arteries in the brain.
7. low blood pressure.
8. seizures.

What biochemical parameters should be checked when a patient is receiving propofol?

The following parameters should be monitored for all patients receiving propofol: pulse oximetry, blood pressure, and electrocardiography and heart rate.

What is the action of propofol?

The action of propofol involves a positive modulation of the inhibitory function of the neurotransmitter gama-aminobutyric acid (GABA) through GABA-A receptors. Rapid – time to onset of unconsciousness is 15-30 seconds, due to rapid distribution from plasma to the CNS.

What are the guidelines in dosing propofol in patient?

Most patients require 1.5 – 9 mg/kg/h Propofol. The infusion may be supplemented by bolus administration of upto 1 mg/kg body weight. if a rapid increase of depth of sedation is required. In ASA III and IV patients lower doses may be required.

How do you administer propofol IV?

Can a nurse administer propofol?

Conclusions: Trained nurses and endoscopists can administer propofol safely for endoscopic procedures. Nurse-administered propofol sedation is one potential solution to the high cost associated with anesthetist-delivered sedation for endoscopy.