What is the meaning of acute interstitial nephritis?
Acute interstitial nephritis (AIN) is a renal lesion that typically causes a decline in kidney function and is characterized by an inflammatory infiltrate in the kidney interstitium [1]. It is most often induced by drug therapy.
How is acute interstitial nephritis treated?
Corticosteroids have been a mainstay of therapy for tubulointerstitial nephritis, but mycophenolate mofetil may also have a role. Ultimately, however, treatment depends on the underlying etiology.
What are the signs and symptoms of nephritis?
What are the symptoms of acute nephritis?
- pain in the pelvis.
- pain or a burning sensation while urinating.
- a frequent need to urinate.
- cloudy urine.
- blood or pus in the urine.
- pain in the kidney area or abdomen.
- swelling of the body, commonly in the face, legs, and feet.
- vomiting.
What are the symptoms of acute interstitial nephritis?
Symptoms of interstitial nephritis
- Increased urine output.
- Blood in your urine or dark urine.
- Nausea or vomiting.
- Fever or rash.
- Elevated blood pressure.
- Changes in mental status, such as drowsiness or confusion.
- Swelling of any area of your body.
- Sudden weight gain. This can be caused by extra fluid in the body.
How is nephritis diagnosed?
A blood test that measures a waste product in the blood called creatinine can also provide information on the health of the kidneys. However, a biopsy is the best way to check for nephritis. For this procedure, a doctor will remove a piece of the kidney with a needle and send it to a laboratory for analysis.
What are symptoms of interstitial nephritis?
Can interstitial nephritis be reversed?
The infection-induced and idiopathic types of acute interstitial nephritis were always reversible. Drug-related acute interstitial nephritis caused permanent renal insufficiency in 36% with a maximum of 56% in NSAID-induced cases.
Can interstitial nephritis be cured?
Chronic tubulointerstitial nephritis has no cure. Some patients may require dialysis. Eventually, a kidney transplant may be needed.