What does the viral genome do?
The virus’s genome is uncoated from the protein and injected into the host cell. Then the viral genome hijacks the host cell’s machinery, forcing it to replicate the viral genome and produce viral proteins to make new capsids. Next, the viral particles are assembled into new viruses.
What is a viral genome made of?
Chemical Composition and Mode of Replication: The genome of a virus may consist of DNA or RNA, which may be single stranded (ss) or double stranded (ds), linear or circular. The entire genome may occupy either one nucleic acid molecule (monopartite genome) or several nucleic acid segments (multipartite genome).
What causes Iridovirus in fish?
The source of the global epizootic of disease caused by systemic iridoviruses in finfish and amphibians is uncertain, but three possibilities are discussed: trade in food fish, trade in ornamental fish, reptiles and amphibians and emergence from unknown reservoir hosts associated with environmental change.
Can Iridovirus infect vertebrates?
Members of the family Iridoviridae (iridovirids) are large dsDNA viruses that infect both invertebrate and vertebrate ectotherms and whose symptoms range in severity from minor reductions in host fitness to systemic disease and large-scale mortality.
How big is the genome of the Iridoviridae?
The genome of the iridovirus is not segmented but contains a single molecule of linear double-stranded DNA. The compelte genome is 150000-280000 nucleotides long. The genome has a guanine+cytosine content of 30%. Double stranded DNA is circularly permutted.
Is the genome of Gryllus bimaculatus iridovirus complete?
The nearly complete genome of Gryllus bimaculatus iridovirus (GbIV) has been sequenced; for the others only the major capsid protein sequence has been determined. Virus names and abbreviations are not official ICTV designations.
Who are the natural hosts of Iridoviridae viruses?
Iridoviridae is a family of viruses with double-stranded DNA genomes. Amphibia, fish, invertebrates, lepidoptera, and orthoptera insects serve as natural hosts. There are currently 12 species in this family, divided among two subfamilies and 5 genera.
Where is the capsid located in an iridovirus?
Virion Structure of an Iridovirus. The virions of iridovirus consist of a capsid and an internal lipid membrane. The capsid is not enveloped. The internal lipid membrane is located between the outer and inner protein shell. The capsid, or nucleocapsid, is round and exhibits icosahedral symmetry. the isometric capsid has a diameter of 120-140nm.