How is ephedrine hydrochloride calculated?
ESTIMATION OF EPHEDRINE HCL. stirring, add about 30 ml acetic anhydride and make up the volume (1000 ml) with glacial acetic acid and keep the mixture for 24 hour. and renders the solution virtually anhydrous. anhydride because reaction between HClO4 and acetic anhydride is explosive.
Which indicator is used in assay of ephedrine HCl by non aqueous titration?
ESTIMATION OF EPHEDRINE HCl A titration is performed against perchloric acid using crystal violet as an indicator.
What is added in the assay of ephedrine HCl?
Assay—Dissolve about 500 mg of Ephedrine Hydrochloride, ac- Ephedrine. Sulfate—Dissolve 100 mg in 40 mL of water, and add 1 mL of mg of C10H15NO · HCl.
Is ephedrine hydrochloride acid or base?
Also, a salt such as ephedrine hydrochloride can be prepared between a weak base-ephedrine and a strong acid-hydrochloric acid.
What is ephedrine hydrochloride?
Ephedrine is a central nervous system stimulant used to treat breathing problems (as a bronchodilator), nasal congestion (as a decongestant), low blood pressure problems (orthostatic hypotension), or myasthenia gravis.
What is the difference between aqueous and nonaqueous titration?
The key difference between aqueous and non-aqueous titration is that aqueous titrations use water as the solvent for dissolving the analyte samples for the titration, whereas non-aqueous titrations use organic solvents for dissolving the sample. A titration process requires a specific apparatus.
Which quantitative determination of ephedrine is carried out by?
A simple, specific, and accurate 1H nuclear magnetic resonance (NMR) spectroscopic method has been developed for quantitative determination of the Ephedra alkaloids (-)-ephedrine, (+)-pseudoephedrine, and (+/-)-norephedrine, either singly or in mixtures with each other.
What is the pH of ephedrine?
The pH range is 4.5 to 7.0. Ephedrine sulfate is a sympathomimetic amine that directly acts as an agonist at α- and ß adrenergic receptors and indirectly causes the release of norepinephrine from sympathetic neurons.
What is ephedrine hydrochloride used for?
What is meant by Levelling effect?
Leveling effect or solvent leveling refers to the effect of solvent on the properties of acids and bases. The strength of a strong acid is limited (“leveled”) by the basicity of the solvent. Similarly the strength of a strong base is leveled by the acidity of the solvent. In water, OH− is the strongest base.
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