What is the most severe type of epilepsy?
Tonic-clonic seizures. Tonic-clonic seizures, previously known as grand mal seizures, are the most dramatic type of epileptic seizure. They can cause an abrupt loss of consciousness and body stiffening, twitching and shaking. They sometimes cause loss of bladder control or biting your tongue.
Can Lennox-Gastaut be cured?
There is no cure for the disorder. Complete recovery, including freedom from seizures and normal development, is very rare. The prognosis for individuals with Lennox-Gastaut syndrome varies. There is no cure for the disorder.
How rare is LGS?
In 1 out of 4 people, no cause can be found. About 2 to 5% of children with epilepsy have LGS. Usually, LGS persists through childhood and adolescence to adult years.
What drugs are approved for Lennox-Gastaut syndrome?
Valproate (valproic acid) is generally considered the first-line therapy for Lennox-Gastaut syndrome because it is effective against a wide spectrum of seizures.
Is topiramate used in Lennox-Gastaut syndrome?
Purpose: The response to topiramate (TPM) as long-term adjunctive therapy was evaluated in patients with Lennox-Gastaut syndrome (LGS) in a long-term, open-label extension to a double-blind, placebo-controlled trial.
What is intractable Lennox-Gastaut syndrome?
Lennox-Gastaut syndrome (LGS) is a type of epilepsy. Patients with LGS experience many different types of seizures including: Tonic – stiffening of the body. Atonic – temporary loss of muscle tone and consciousness, causing the patient to fall.
How much topiramate should I take for migraines?
The recommended dosage of topiramate for migraine prevention is 50 mg twice per day. Patients should start with 25 mg once per day, then increase by 25 mg per week up to the recommended dosage.
Can Lennox-Gastaut syndrome cause death?
People with Lennox-Gastaut syndrome have a higher risk of death than their peers of the same age. Although the increased risk is not fully understood, it is partly due to poorly controlled seizures and injuries from falls.