What is the mode of action of Levosulpiride?
The main mechanism of action of levosulpiride consists of blocking the D2 dopaminergic receptors, preferentially located on the presynaptic membranes in the dopaminergic pathways of the brain; this means that sulpiride is a selective autoreceptor blocker.
What is the function of Lesuride?
Lesuride Tablet is used in the treatment of gastric problems like nausea, vomiting, heartburn, or indigestion. It also prevents acid reflux (acid going up to the food pipe) and hence helps in the treatment of gastroesophageal reflux disease (GERD).
What is the benefit of Levosulpiride?
Levosulpiride is used for the treatment of upper abdominal pain and bloating, nausea, vomiting, irritable bowel movement, irregular emptying of the stomach in diabetic patients, It is also used for the treatment of depression and schizophrenia in adults.
Is levosulpiride a dopamine antagonist?
Levosulpiride is a sulpiride isomer that exerts its prokinetic action through a dual mechanism: 1) as a D(2) dopamine receptor antagonist and 2) as a serotonin 5HT(4) receptor agonist, conferring this drug with a cholinergic effect.
Which is better itopride vs levosulpiride?
In present study, the efficacy of levosulpiride was compared to itopride in relieving symptoms. It was comparable in efficacy to itopride in relieving symptoms was well tolerated and devoid of much adverse effects. The rate of treatment success was better with levosulpiride than itopride.
Is levosulpiride safe?
In conclusion, levosulpiride is an effective and safe drug in the treatment of dysmotility-like functional dyspepsia and non-erosive reflux disease.
Can I take levosulpiride after meal?
Tablet LEVAZEO SR 75 to be taken before or after meal. Due to Neuroleptic malignant syndrome one with esophaguse problem should not take lesuride.
How long one can take levosulpiride?
Levosulpiride was administered during 4 weeks according to the conditions of use established in the product’s technical form in any of the two available presentations (tablets or oral solution formulation). The duration of the study was 8 weeks (4-week treatment period and 4-week follow-up period).
Can we take levosulpiride after meal?