What are the symptoms of Hypogammaglobulinemia?
Hypogammaglobulinemia is a problem with the immune system that prevents it from making enough antibodies called immunoglobulins….Which symptoms you or your child has will depend on what infections you get, but they can include:
- coughing.
- sore throat.
- fever.
- ear pain.
- congestion.
- sinus pain.
- diarrhea.
- nausea and vomiting.
What is the cause of Hypogammaglobulinemia?
The most common cause is common variable immunodeficiency (CVID). Causes of secondary hypogammaglobulinemia include gastrointestinal losses (e.g., malabsorption/protein-losing enteropathy), nephrotic syndrome, hematologic malignancy, and medication (e.g., immunosuppressives, such as corticosteroids and chemotherapy).
What happen if IgE is high?
The blood usually has small amounts of IgE antibodies. Higher amounts can be a sign that the body overreacts to allergens, which can lead to an allergic reaction. IgE levels can also be high when the body is fighting an infection from a parasite and from some immune system conditions.
Is hypogammaglobulinemia an autoimmune disease?
Many autoimmune diseases have been described in the course of hypogammaglobulinemia, such as cytopenias, inflammatory bowel disease, seronegative arthritis, Sjögren’s syndrome, uveitis, vasculitis, and vitiligo (22,23).
Is hypogammaglobulinemia a autoimmune disease?
What was Job’s skin disease?
Hyperimmunoglobulin E syndrome is also called Job syndrome. It is named after the biblical character Job, whose faithfulness was tested by an affliction with draining skin sores and pustules. People with this condition have long-term, severe skin infections.
What is Joubert syndrome?
Joubert syndrome (JS) is an autosomal recessive genetic disorder that affects the area of the brain that controls balance and coordination known as the cerebellum.