What are satellite animals?
Satellite animals are extra animals dosed as per protocol but not subjected to toxicological and pathological observations and tests. Instead, they are used exclusively for the evaluation of pharmacokinetic characteristics of the test compound.
What is Tk sampling?
TK describes the use of bioanalytical sampling to characterize the disposition of a target compound during time-course toxicity studies in animals. TK is closely related to PK, which is defined as the process of drug absorption, distribution, metabolism, and excretion (ADME) in a living organism.
What is a toxicokinetic study?
Toxicokinetics refers to the study of absorption, distribution, metabolism/biotransformation, and excretion (ADME) of toxicants/xenobiotics in relation to time.
What is a satellite group?
A satellite constellation is a group of artificial satellites working together as a system. Unlike a single satellite, a constellation can provide permanent global or near-global coverage, such that at any time everywhere on Earth at least one satellite is visible. They may also use inter-satellite communication.
How are satellites used in wildlife monitoring?
Combining animal tracking with Earth observation (EO) data is fundamental to studying an animal’s population ecology and behaviour. It provides several options for extracting data, and user-defined solutions for temporal and spatial resolution. …
What is toxicokinetics and Toxicodynamics?
Toxicokinetics describes how a toxicant (i.e., a poison) enters the body and reaches a target tissue. Toxicodynamics describes what happens to that tissue once the toxicant reaches an effective dose. Susceptibility to toxicants changes during development.
What is TK and PK?
PK is the abbreviation for pharmacokinetics. TK is the abbreviation for toxicokinetics. Pharmacokinetics generally deals with doses that are in a therapeutic range. Thus common dose ranges will include the no pharmacologic effect level on the low end, and the maximum pharmacologic effect level on the high end.
What is difference between PK and TK?
PK is the abbreviation for pharmacokinetics. TK is the abbreviation for toxicokinetics. Pharmacokinetics generally deals with doses that are in a therapeutic range.
What are 3 types of toxicology?
The field of forensic toxicology involves three main sub-disciplines: postmortem forensic toxicology, human performance toxicology, and forensic drug testing. These specialized fields offer a variety of exciting career paths.